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Joint disruption of Ret and Ednrb transcription shifts cell fate trajectories in the enteric nervous system in Hirschsprung disease

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2507062122Source: DataRank Database

Joint disruption of Ret and Ednrb transcription shifts cell fate trajectories in the enteric nervous system in Hirschsprung disease is a research paper published in Proceedings of the National Academy of Sciences (2025). On theSindex it has a DataRank of 0.104. It has been cited 1 time.

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0.104DataRank · unranked

Scored on demand from live citation data

Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)Impact (FWCI 1.02)OA: hybridTopics (39)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.104

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

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Authors (5)

Rebecca Chubaryov,Mingzhou Fu ORCID,Gabriel Grullon,Aravinda Chakravarti ORCID,Ryan D. Fine ORCID

Live enrichment

PubMed:41118220 OpenAlex:https://openalex.org/W4415400742

NIH

Grant: HD028088

NYULH

Grant: NA

FWCI

1.02

Citation Percentile

0.8%

Citation Trend

2026

hybridLicense: cc-by-nc-nd

journalhttps://doi.org/10.1073/pnas.2507062122

publisherhttps://doi.org/10.1073/pnas.2507062122

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2507062122

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41118220

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12582274/

Fields of Study

Congenital gastrointestinal and neural anomaliesIntestinal Malrotation and Obstruction DisordersCongenital Anomalies and Fetal SurgeryHirschsprung DiseaseAnimalsProto-Oncogene Proteins c-retEnteric Nervous SystemMiceReceptor, Endothelin BDisease Models, AnimalGene Regulatory NetworksNeural CrestTranscription, GeneticNeurons

MeSH Terms

AnimalsDisease Models, AnimalHirschsprung DiseaseNeural CrestNeuronsTranscription, GeneticEnteric Nervous SystemReceptor, Endothelin BProto-Oncogene Proteins c-retMiceGene Regulatory Networks

Keywords

Enteric nervous systemAlleleGeneCell fate determinationGene expressionReceptorRegulation of gene expressionNervous systemCellEdnrbRetaganglionosiscell fateepistasis