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CDKN1B (p27/kip1) enhances drug-tolerant persister CTCs by restricting polyploidy following mitotic inhibitors

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2507203122Source: DataRank Database

CDKN1B (p27/kip1) enhances drug-tolerant persister CTCs by restricting polyploidy following mitotic inhibitors is a research paper published in Proceedings of the National Academy of Sciences (2025). On theSindex it has a DataRank of 0.165. It has been cited 2 times.

N/A

0.165DataRank · unranked

Scored on demand from live citation data

Open Access2 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 1.11)OA: hybridTopics (60)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.165

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

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Authors (20)

Taronish D. Dubash,Annamária Szabolcs ORCID,Ben S. Wittner ORCID,Johannes Kreuzer ORCID,Robert Morris ORCID

Live enrichment

PubMed:40623195 PMC:PMC12280942 OpenAlex:https://openalex.org/W4412073629

Howard Hughes Medical Institute

Grant: na

HHS | National Institutes of Health

Grant: R01CA129933

National Institutes of Health

Grant: 5R01CA129933-13

Modeling Metastasis and Acquired Drug Resistance Using Circulating Tumor Cells

FWCI

1.11

Citation Percentile

0.8%

Citation Trend

2026

hybridLicense: cc-by-nc-nd

journalhttps://www.pnas.org/doi/pdf/10.1073/pnas.2507203122

publisherhttps://www.pnas.org/doi/pdf/10.1073/pnas.2507203122

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2507203122

journalhttps://doi.org/10.1073/pnas.2507203122

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40623195

Fields of Study

Microtubule and mitosis dynamicsCancer Cells and MetastasisCancer-related Molecular Pathways03 medical and health sciences0302 clinical medicineHumansBreast NeoplasmsFemalePolyploidyCyclin-Dependent Kinase Inhibitor p27Neoplastic Cells, CirculatingDocetaxelMitosisDrug Resistance, NeoplasmCell Line, TumorTaxoidsAntineoplastic Agents

MeSH Terms

DocetaxelAntineoplastic AgentsBreast NeoplasmsFemaleHumansMitosisNeoplastic Cells, CirculatingPolyploidyDrug Resistance, NeoplasmTaxoidsCell Line, TumorCyclin-Dependent Kinase Inhibitor p27

Keywords

Cancer researchMitosisCell cyclePaclitaxelMultidrug toleranceBiologyMetastatic breast cancerPopulationDocetaxelBreast cancerCancerCancer cellPharmacologyCell biologyMedicineGeneticsTaxanesCirculating Tumor CellsCdkn1bDrug-tolerant Persister CellsBreast NeoplasmsAntineoplastic AgentsBiological SciencesNeoplastic Cells, CirculatingPolyploidyDrug Resistance, NeoplasmCell Line, TumorHumansFemaleTaxoidsCyclin-Dependent Kinase Inhibitor p27

Sustainable Development Goals

SDG 0: Good health and well-being