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Glycosaminoglycans activate peptidylarginine deiminase 4 by enhancing calcium affinity

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2508369122Source: DataRank Database

Glycosaminoglycans activate peptidylarginine deiminase 4 by enhancing calcium affinity is a research paper published in Proceedings of the National Academy of Sciences (2025). On theSindex it has a DataRank of 0.104. It has been cited 1 time, with 1 citing works in its 1-hop citation network.

N/A

0.104DataRank · unranked

Scored on demand from live citation data

Open Access1 citations · 1 citing works in its network

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Linked data & code

refseq pdb

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 1.58)OA: hybridTopics (23)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.104

From this paper's citation signal

Citation Network Contribution

From 0 citing papers with measurable signal

This paper's DataRank is currently driven only by its base citation score. None of the citing papers had measurable citation signal.

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Authors (15)

Ewa Bielecka ORCID,Karolina Marzec,Łukasz Pijanowski ORCID,Artur Biela ORCID,P. Wilk ORCID

Live enrichment

PubMed:41166417 PMC:PMC12595441 OpenAlex:https://openalex.org/W4415706861

EEA Grants/Norway Grants

Grant: 2019/34/H/NZ1/00674

Polish Ministry of Higher Education

Grant: 1/SOL/2021/2

National Science Centre Poland

Grant: 2018/30/M/NZ1/00367

Research Council of Norway and NIH

Grant: 296129

National Science Centre Poland

Grant: 2024/53/B/NZ5/01005

NIGMS NIH HHS

Grant: R01 GM129325

FWCI

1.58

Citation Percentile

0.9%

Influential Citations

Citation Trend

2026

hybridLicense: cc-by

journalhttps://www.pnas.org/doi/pdf/10.1073/pnas.2508369122

HYBRIDhttps://www.pnas.org/doi/pdf/10.1073/pnas.2508369122

publisherhttps://www.pnas.org/doi/pdf/10.1073/pnas.2508369122

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2508369122

journalhttps://doi.org/10.1073/pnas.2508369122

Fields of Study

Rheumatoid Arthritis Research and TherapiesOsteoarthritis Treatment and MechanismsHER2/EGFR in Cancer ResearchMedicineChemistry

MeSH Terms

Protein-Arginine DeiminasesProtein-Arginine Deiminase Type 4Arthritis, RheumatoidCalciumEnzyme ActivationGlycosaminoglycansHumans

Keywords

CitrullinationGlycosaminoglycanEnzymeCalciumArginineCalcium metabolismMechanism of actionMechanism (biology)Rheumatoid arthritisPad4Peptidylarginine Deiminase

Glycosaminoglycans activate peptidylarginine deiminase 4 by enhancing calcium affinity

FAIR Checklist

DataRank Breakdown

Authors (15)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)