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NPC1 trafficking via VPS41-dependent LAMP carriers regulates endosomal cholesterol homeostasis

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2521979122Source: DataRank Database

NPC1 trafficking via VPS41-dependent LAMP carriers regulates endosomal cholesterol homeostasis is a research paper published in Proceedings of the National Academy of Sciences (2025). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Open Access2 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (8 grants)OA: hybridTopics (31)IDs (PubMed)

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Authors (11)

Matteo Tantucci,Paolo Sanza,Kristian Zubak,Giorgia Marodin ORCID,Jenina Kingma ORCID

Live enrichment

PubMed:41452985

EC | Horizon Europe | Excellent Science | HORIZON EUROPE Marie Sklodowska-Curie Actions

Grant: 953489

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Grant: 184.034.014

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Grant: 016.176.643

NWO | Exacte en Natuurwetenschappen

Grant: M.22.034

ZonMw

Grant: 09120242410013

Welch Foundation

Grant: I-2246-20250403

HHS | NIH

Grant: R00GM141261

HHS | NIH

Grant: R01GM155152

hybridLicense: cc-by-nc-nd

publisherhttps://www.pnas.org/doi/pdf/10.1073/pnas.2521979122

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2521979122

repositoryhttps://pure.amsterdamumc.nl/ws/files/180195977/Npc1-trafficking-via-vps41-dependent-lamp-carriers-regulates-endosomal-cholesterol-homeostasis.pdf

repositoryhttps://dspace.library.uu.nl/handle/1874/469049

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12772203/

Fields of Study

HumansCholesterolVesicular Transport ProteinsHeLa CellsEndosomesHomeostasisLysosomesLysosomal Membrane ProteinsIntracellular Signaling Peptides and ProteinsProtein TransportNiemann-Pick C1 ProteinNiemann-Pick Disease, Type CLysosomal-Associated Membrane Protein 1

MeSH Terms

Keywords

NPC1VPS41cholesterol metabolismintracellular cholesterol transportlysosomes