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Identification of an IRF–ZBP1–caspase-8–NINJ1 axis in driving PANoptosis and pathology during alcohol-associated liver disease

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2525296122Source: DataRank Database

Identification of an IRF–ZBP1–caspase-8–NINJ1 axis in driving PANoptosis and pathology during alcohol-associated liver disease is a research paper published in Proceedings of the National Academy of Sciences (2025). On theSindex it has a DataRank of 0. It has been cited 10 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access10 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (7 grants)Impact (FWCI 8.17)OA: hybridTopics (28)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Wen Chen ORCID,Clay D. King,Sivakumar Prasanth Kumar ORCID,Chadi A. El Farran ORCID,Peter Vogel ORCID

Live enrichment

PubMed:41359840 PMC:PMC12718386 OpenAlex:https://openalex.org/W4417134430

HHS | NIH

Grant: AI101935

HHS | NIH

Grant: AI124346

HHS | NIH

Grant: AI160179

HHS | NIH

Grant: AR056296

HHS | NIH

Grant: CA253095

HHS | NIH | National Institute of General Medical Sciences

Grant: P20GM144269

American Lebanese Syrian Associated Charities

Grant: N/A

FWCI

8.17

Citation Percentile

1.0%

Citation Trend

2026

hybridLicense: cc-by-nc-nd

journalhttps://doi.org/10.1073/pnas.2525296122

publisherhttps://doi.org/10.1073/pnas.2525296122

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2525296122

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41359840

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12718386/

Fields of Study

Alcohol Consumption and Health EffectsInflammasome and immune disordersAlcoholism and Thiamine Deficiency

MeSH Terms

AnimalsHumansImmunity, InnateLiver Diseases, AlcoholicMaleMice, Inbred C57BLRNA-Binding ProteinsMice, KnockoutHepatocytesInterferon Regulatory FactorsMiceCaspase 8

Keywords

Innate immune systemContext (archaeology)Immune systemInflammationProgrammed cell deathProinflammatory cytokineDownregulation and upregulationInflammasomeLiver injuryCaspaseAlcoholZbp1Alcohol-associated Liver Disease

Identification of an IRF–ZBP1–caspase-8–NINJ1 axis in driving PANoptosis and pathology during alcohol-associated liver disease

FAIR Checklist

Authors (8)

Funding (7 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)