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Identifying genome-by-childhood trauma interactions for depression using a forest-based approach in the UK Biobank and Adolescent Brain Cognitive Development Study

Proceedings of the National Academy of Sciences(2026)10.1073/pnas.2527955123Source: DataRank Database

Identifying genome-by-childhood trauma interactions for depression using a forest-based approach in the UK Biobank and Adolescent Brain Cognitive Development Study is a research paper published in Proceedings of the National Academy of Sciences (2026). On theSindex it has a DataRank of 0.

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Enrichment:Funding (6 grants)Impact (FWCI 0.00)OA: hybridTopics (50)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

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Context only (not used in score)

Findable (1/2)

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Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Jeffrey R. Gruen ORCID,Heping Zhang ORCID,Fēi Dèng ORCID,Yue Hu ORCID

Live enrichment

PubMed:41650220 PMC:PMC12890833 OpenAlex:https://openalex.org/W7128216179

HHS | NIH | National Institute on Aging

Grant: P30AG021342-22S1

HHS | NIH | National Human Genome Research Institute

Grant: R01HG010171

NSF | Directorate for Mathematical and Physical Sciences

Grant: DMS-2112711

NICHD NIH HHS

Grant: P50 HD027802

NICHD NIH HHS

Grant: P50 HD052120

NICHD NIH HHS

Grant: T32 HD007149

FWCI

0.00

Citation Percentile

0.1%

hybridLicense: cc-by-nc-nd

journalhttps://doi.org/10.1073/pnas.2527955123

publisherhttps://doi.org/10.1073/pnas.2527955123

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2527955123

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41650220

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12890833/

Fields of Study

Genetic Associations and EpidemiologyMental Health Research TopicsPosttraumatic Stress Disorder ResearchHumansGene-Environment InteractionPolymorphism, Single NucleotideDepressionGenome-Wide Association StudyUK BiobankUnited KingdomFemaleMaleAdolescentGenetic Predisposition to DiseaseCognitionBrainGenetic Risk Score

MeSH Terms

Machine LearningAdverse Childhood ExperiencesGenetic Risk ScoreUK BiobankAdolescentAdultBrainChildCognitionDepressionFemaleUnited KingdomHumansMaleMiddle AgedBiological Specimen BanksGenetic Predisposition to DiseaseMultifactorial InheritancePolymorphism, Single NucleotideGenome-Wide Association StudyGene-Environment Interaction

Keywords

BiobankDepression (economics)HeritabilityCognitionBrain developmentEarly childhoodMajor depressive disorderPolygenic risk scoreDepressionRandom ForestGene–environment InteractionChildhood Trauma

Sustainable Development Goals

SDG 0: Life in Land

Identifying genome-by-childhood trauma interactions for depression using a forest-based approach in the UK Biobank and Adolescent Brain Cognitive Development Study

FAIR Checklist

Authors (4)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)