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P450c11B3 mRNA, Transcribed from a Third P450c11 Gene, Is Expressed in a Tissue-specific, Developmentally, and Hormonally Regulated Fashion in the Rodent Adrenal and Encodes a Protein with Both 11-Hydroxylase and 18-Hydroxylase Activities

Journal of Biological Chemistry(1995)10.1074/jbc.270.4.1643Source: DataRank Database

P450c11B3 mRNA, Transcribed from a Third P450c11 Gene, Is Expressed in a Tissue-specific, Developmentally, and Hormonally Regulated Fashion in the Rodent Adrenal and Encodes a Protein with Both 11-Hydroxylase and 18-Hydroxylase Activities is a research paper published in Journal of Biological Chemistry (1995). On theSindex it has a DataRank of 3.8. It has been cited 63 times, with 59 citing works in its 1-hop citation network.

N/A

3.8DataRank · unranked

Scored on demand from live citation data

63 citations · 59 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)Impact (FWCI 4.67)OA: hybridTopics (84)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 17%Citation Network 83%

Base Score Contribution

0.624

From this paper's citation signal

Citation Network Contribution

3.1

From 51 citing papers with measurable signal

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Authors (3)

Susanna R. Bair,Helena Monis,Synthia H. Mellon

Live enrichment

PubMed:7829497 OpenAlex:https://openalex.org/W2009364340

NICHD NIH HHS

Grant: HD27970

NICHD NIH HHS

Grant: HD11979

FWCI

4.67

Citation Percentile

1.0%

Citation Trend

2013

2014

2015

2016

2018

2026

hybridLicense: cc-by

journalhttps://doi.org/10.1074/jbc.270.4.1643

publisherhttps://doi.org/10.1074/jbc.270.4.1643

publisherhttps://api.elsevier.com/content/article/PII:S0021925818854047?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925818854047?httpAccept=text/plain

publisherhttps://syndication.highwire.org/content/doi/10.1074/jbc.270.4.1643

Fields of Study

Hormonal Regulation and HypertensionPharmacogenetics and Drug MetabolismEstrogen and related hormone effectsAdrenal GlandsAgingAmino Acid SequenceAnimalsBase SequenceCloning, MolecularCytochrome P-450 CYP11B2Cytochrome P-450 Enzyme SystemDNA PrimersDNA, ComplementaryEmbryonic and Fetal DevelopmentFemaleFetusGene Expression Regulation, EnzymologicIn Situ HybridizationMaleMolecular Sequence DataOligonucleotides, AntisenseOrgan SpecificityPolymerase Chain ReactionRNA, MessengerRatsRats, Sprague-DawleyRestriction MappingSequence Homology, Amino AcidSequence Homology, Nucleic AcidSex CharacteristicsSex FactorsSteroid 11-beta-HydroxylaseSubstrate SpecificityTranscription, Genetic

MeSH Terms

Adrenal GlandsAgingAmino Acid SequenceAnimalsBase SequenceCloning, MolecularCytochrome P-450 Enzyme SystemFemaleEmbryonic and Fetal DevelopmentFetusMaleMolecular Sequence DataOrgan SpecificityRNA, MessengerSequence Homology, Nucleic AcidSex CharacteristicsSex FactorsSteroid 11-beta-HydroxylaseSubstrate SpecificityTranscription, GeneticRestriction MappingGene Expression Regulation, EnzymologicPolymerase Chain ReactionOligonucleotides, AntisenseRats, Sprague-DawleySequence Homology, Amino AcidIn Situ HybridizationDNA PrimersDNA, ComplementaryCytochrome P-450 CYP11B2Rats

Keywords

Zona glomerulosaAldosterone synthaseSteroid 11-beta-hydroxylaseZona fasciculataCorticosteroneBiologyMessenger RNAAdrenal glandAldosteroneGeneComplementary DNAMolecular biologyEndocrinologyInternal medicineGeneticsRenin–angiotensin systemSteroidAngiotensin IIHormone