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mTOR kinase inhibition disrupts neuregulin 1-ERBB3 autocrine signaling and sensitizes NF2-deficient meningioma cellular models to IGF1R inhibition

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.014960Source: DataRank Database

mTOR kinase inhibition disrupts neuregulin 1-ERBB3 autocrine signaling and sensitizes NF2-deficient meningioma cellular models to IGF1R inhibition is a research paper published in Journal of Biological Chemistry (2020). On theSindex it has a DataRank of 0. It has been cited 18 times.

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Open Access18 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)OA: goldTopics (24)IDs (PubMed)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Serkan Erdin ORCID,Luke Witt,Justin T. Jordan ORCID,Scott R. Plotkin ORCID,James F. Gusella ORCID

Live enrichment

PubMed:33273014

National Institutes of Health

Grant: 5R01NS113854-04

NF2-Associated Meningiomas: From Omics Discovery to Targeted Therapy

National Health and Medical Research Council (NHMRC)

Grant: 113854

Neural Mechanisms in Tactile, Kinaesthetic and Pain Sensation

goldLicense: CC BY

publisherhttps://api.elsevier.com/content/article/PII:S0021925820001507?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925820001507?httpAccept=text/plain

publisherhttps://syndication.highwire.org/content/doi/10.1074/jbc.RA120.014960

https://doi.org/10.1074/jbc.ra120.014960

http://www.jbc.org/article/S0021925820001507/pdf

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

BenzoxazolesNeurofibromin 2Dose-Response Relationship, DrugMorpholinesNeuregulin-1Receptor, EphA2LapatinibAntibodies, Monoclonal, HumanizedAutocrine CommunicationPyrimidinesGene Expression RegulationCell MovementCell Line, TumorBenzamidesMeningeal NeoplasmsHumansPyrazolesMeningiomaProto-Oncogene Proteins c-aktResearch ArticleCell Proliferation