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The short third intracellular loop and cytoplasmic tail of bitter taste receptors provide functionally relevant GRK phosphorylation sites in TAS2R14

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.016056Source: DataRank Database

The short third intracellular loop and cytoplasmic tail of bitter taste receptors provide functionally relevant GRK phosphorylation sites in TAS2R14 is a research paper published in Journal of Biological Chemistry (2020). On theSindex it has a DataRank of 0. It has been cited 8 times.

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Open Access8 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)OA: hybridTopics (51)IDs (PubMed, PMC)

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Authors (5)

Maria A. Castaño,Lauren K. Lujan ORCID,Jung A. Woo ORCID,Stephen B. Liggett ORCID,Donghwa Kim ORCID

Live enrichment

PubMed:33465377 PMC:PMC7949105

National Institutes of Health

Grant: HL114471

National Institutes of Health

Grant: HL155532

NHLBI NIH HHS

Grant: R01 HL155532

NHLBI NIH HHS

Grant: P01 HL114471

National Institutes of Health

Grant: 5R01HL155532-04

Characterization of biased airway smooth muscle TAS2R agonists for treating asthma

National Institutes of Health

Grant: 3P01HL114471-08S2

Novel Molecular Mechanisms Promote GPCR-Induced Bronchodilation in Asthma

hybridLicense: cc-by

publisherhttp://www.jbc.org/article/S0021925820002124/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925820002124?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925820002124?httpAccept=text/plain

publisherhttps://syndication.highwire.org/content/doi/10.1074/jbc.RA120.016056

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7949105

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

BronchiEndosomesMyocytes, Smooth MuscleHumansCalciumDiphenhydramineGreen Fluorescent ProteinsReceptors, G-Protein-CoupledVesicular Transport ProteinsRecombinant Fusion ProteinsRNA, Small InterferingAmino Acid SubstitutionTachyphylaxisProtein Processing, Post-TranslationalProtein BindingPhosphorylationMutationGenes, ReporterG-Protein-Coupled Receptor Kinase 2HEK293 Cellsbeta-ArrestinsTaste Receptors, Type 2

Keywords

DesensitizationΒ-arrestinG Protein–coupled ReceptorsTas2rG Protein–coupled Receptor KinasesG-Protein-Coupled Receptor Kinase 2Recombinant Fusion ProteinsGreen Fluorescent ProteinsMyocytes, Smooth MuscleVesicular Transport ProteinsBronchiEndosomesReceptors, G-Protein-CoupledDiphenhydramineHEK293 CellsAmino Acid SubstitutionGenes, ReporterMutationHumansCalciumPhosphorylationRNA, Small InterferingTachyphylaxisProtein Processing, Post-TranslationalResearch ArticleProtein Binding