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Synaptic restoration by cAMP/PKA drives activity-dependent neuroprotection to motoneurons in ALS

The Journal of Experimental Medicine(2020)10.1084/jem.20191734Source: DataRank Database

Synaptic restoration by cAMP/PKA drives activity-dependent neuroprotection to motoneurons in ALS is a research paper published in The Journal of Experimental Medicine (2020). On theSindex it has a DataRank of 0. It has been cited 83 times.

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Open Access83 citations

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Enrichment:Funding (21 grants)Impact (FWCI 3.35)OA: greenTopics (62)Linked Datasets (8)DataCite Reuse (8)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

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Context only (not used in score)

Findable (2/2)

Has DOI
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Accessible (1/2)

Open Access

Interoperable (2/2)

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Reusable (0/3)

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Authors (12)

Najwa Ouali Alami ORCID,Nicolas Delestrée ORCID,Clémence Martinot,Linyun Tang,Barbara Commisso

Live enrichment

PubMed:32484501 PMC:PMC7398175 OpenAlex:https://openalex.org/W3032721741

National Institute of Neurological Disorders and Stroke

Grant: R01NS077863

Deutsche Forschungsgemeinschaft

Grant: SFB1149

Deutsche Forschungsgemeinschaft

Grant: 431995586

Deutsche Forschungsgemeinschaft

Grant: RO-5004/8-1

German Ministry of Education and Research

Grant: FKZ 01EW1705A

National Institutes of Health

Grant: 5R01NS077863-02

Electrical and mechanical properties of motor units in a mouse model of ALS

Deutsche Forschungsgemeinschaft

Grant: unidentified

unidentified

Cellular and Molecular Mechanisms in Aging Research Training Group

Fondation Thierry Latran

Université Paris Descartes

Association Française contre les Myopathies

International Graduate School in Molecular Medicine

Radala Foundation for ALS Research

Stiftung Synapsis - Alzheimer Forschung Schweiz AFS

Target ALS

National Institutes of Health

Program Hubert Curien “Polonium”

Medical School Baustein

Universität Ulm

Association pour la Recherche sur la Sclérose Latérale Amyotrophique et autres Maladies du Motoneurone

Chinese Science Council

FWCI

3.35

Citation Percentile

0.9%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

greenLicense: other-oa

repositoryhttps://hal.science/hal-03000058

publisherhttps://rupress.org/jem/article-pdf/doi/10.1084/jem.20191734/1769054/jem_20191734.pdf

journalhttps://doi.org/10.1084/jem.20191734

repositoryhttps://pubmed.ncbi.nlm.nih.gov/32484501

Fields of Study

Amyotrophic Lateral Sclerosis ResearchIon channel regulation and functionNeuroscience and Neuropharmacology Research0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

NeuroprotectionSuperoxide Dismutase-1Amyotrophic Lateral SclerosisAnimalsHumansMice, TransgenicMotor NeuronsSynapsesSignal TransductionCyclic AMP-Dependent Protein KinasesMice

Keywords

NeuroscienceExcitatory postsynaptic potentialPostsynaptic potentialNeuroprotectionAmyotrophic lateral sclerosisAMPA receptorBiologyStimulationNeurotransmissionChemistryGlutamate receptorMedicineInhibitory postsynaptic potentialInternal medicineReceptorAmyotrophic Lateral Sclerosis: enzymologyAmyotrophic Lateral Sclerosis: geneticsGluR subunitsMice, TransgenicArticleMotor Neurons: pathologyMiceSuperoxide Dismutase-1Synapses: enzymologyAnimalsHumansinfo:eu-repo/classification/ddc/610Motor NeuronsSynapses: geneticsIa proprioceptive afferents[SDV.NEU.NB] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/NeurobiologySOD1 protein, humanAmyotrophic Lateral Sclerosis: pathologySynapses: pathologyCyclic AMP-Dependent Protein KinasesCyclic AMP-Dependent Protein Kinases: geneticsSuperoxide Dismutase-1: geneticsSuperoxide Dismutase-1: metabolismSynapsesMotor Neurons: enzymologyMedial longitudinal fasciculusChemogeneticsIn vivo electrophysiological recordingsCyclic AMP-Dependent Protein Kinases: metabolismSignal Transduction

Sustainable Development Goals

SDG 0: Life in Land

Additional file 3 of Patterns of synaptic loss in human amyotrophic lateral sclerosis spinal cord: a clinicopathological study

10.6084/m9.figshare.26606368figshare

Additional file 2 of Patterns of synaptic loss in human amyotrophic lateral sclerosis spinal cord: a clinicopathological study

10.6084/m9.figshare.26606365.v1figshare

Additional file 4 of Patterns of synaptic loss in human amyotrophic lateral sclerosis spinal cord: a clinicopathological study

10.6084/m9.figshare.26606371.v1figshare

Additional file 1 of Patterns of synaptic loss in human amyotrophic lateral sclerosis spinal cord: a clinicopathological study

10.6084/m9.figshare.26606362.v1figshare

Additional file 3 of Patterns of synaptic loss in human amyotrophic lateral sclerosis spinal cord: a clinicopathological study

10.6084/m9.figshare.26606368.v1figshare