Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican

The Journal of Experimental Medicine(2020)10.1084/jem.20200140Source: DataRank Database

Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican is a research paper published in The Journal of Experimental Medicine (2020). On theSindex it has a DataRank of 0. It has been cited 49 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access49 citations

Download PDF

Cite:

Linked data & code

doi

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (20 grants)Impact (FWCI 2.59)OA: bronzeTopics (74)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (30)

Alan T. Tang ORCID,Matthew R. Detter ORCID,Jaesung P. Choi ORCID,Rui Wang ORCID,Xi Yang ORCID

Live enrichment

PubMed:32648916 PMC:PMC7537394 OpenAlex:https://openalex.org/W3041927140

National Institutes of Health

Grant: R01HL094326

National Institutes of Health

Grant: P01NS092521

National Institutes of Health

Grant: T32GM008076

National Institutes of Health

Grant: F31NS115256

National Institutes of Health

Grant: F30NS100252

National Institutes of Health

Grant: T32GM007171

National Institutes of Health

Grant: F30HL140871

National Institutes of Health

Grant: R01HL136507

American Heart Association

Grant: 18PRE34060061

National Natural Science Foundation of China

Grant: 81771240

Australian National Health and Medical Research Council

Grant: APP1124011

National Institutes of Health

Grant: 5P01NS092521-03

Signaling Aberrations and Cerebral Cavernous Malformation Pathogenesis

National Institutes of Health

Grant: 5F30HL140871-02

Investigating the Molecular Pathways of Cerebral Cavernous Malformation Maturation

National Institutes of Health

Grant: 1R01HL094326-01

Heg-CCM Signaling in Cardiovascular Development and Disease

National Institutes of Health

Grant: 1F30NS100252-01

The molecular pathogenesis of cerebral cavernous malformations

National Institutes of Health

Grant: 5T32GM008076-12

PREDOCTORAL TRAINING PROGRAM IN PHARMACOLOGY

National Health and Medical Research Council (NHMRC)

Grant: 1124011

Coupling the mechanical, signalling and transcriptional mechanisms that initiate pathogenesis of Cerebral Cavernous Malformation

National Institutes of Health

Grant: 1F31NS115256-01

Investigating the molecular determinants of cerebral cavernous malformations downstream of MEKK3-KLF2/4 signaling

National Institutes of Health

Grant: 5T32GM007171-17

MEDICAL SCIENTIST

National Institutes of Health

Grant: 5R01HL136507-04

CCM3-mediated exocytosis in pathogenesis of cerebral cavernous malformation

FWCI

2.59

Citation Percentile

0.9%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

bronzeLicense: CC BY NC SA

journalhttps://rupress.org/jem/article-pdf/217/10/e20200140/1050481/jem_20200140.pdf

publisherhttps://rupress.org/jem/article-pdf/217/10/e20200140/1050481/jem_20200140.pdf

publisherhttps://rupress.org/jem/article-pdf/doi/10.1084/jem.20200140/1823122/jem_20200140.pdf

journalhttps://doi.org/10.1084/jem.20200140

repositoryhttps://pubmed.ncbi.nlm.nih.gov/32648916

Fields of Study

Vascular Malformations Diagnosis and TreatmentIntracerebral and Subarachnoid Hemorrhage ResearchIntracranial Aneurysms: Treatment and Complications0301 basic medicine0303 health sciences03 medical and health sciencesADAMTS1 ProteinADAMTS4 ProteinADAMTS5 ProteinAnimalsDisease Models, AnimalEndothelium, VascularFemaleGenetic Association StudiesHemangioma, Cavernous, Central Nervous SystemMaleMiceMice, Inbred C57BLMice, Inbred DBAProteolysisVersicansWhite Matter

MeSH Terms

ADAMTS1 ProteinADAMTS5 ProteinADAMTS4 ProteinAnimalsDisease Models, AnimalEndothelium, VascularFemaleMaleMice, Inbred C57BLMice, Inbred DBAHemangioma, Cavernous, Central Nervous SystemMiceVersicansGenetic Association StudiesProteolysisWhite Matter

Keywords

VersicanProteolysisCell biologyPathogenesisExtracellular matrixLesionKLF2ChemistryEndothelial stem cellEndotheliumImmunologyBiologyTranscription factorProteoglycanPathologyMedicineEndocrinologyBiochemistryIn vitroGeneMaleHemangioma, Cavernous, Central Nervous SystemWhite MatterArticleMice, Inbred C57BLDisease Models, AnimalMiceVersicansADAMTS1 ProteinMice, Inbred DBAADAMTS4 ProteinAnimalsFemaleADAMTS5 ProteinEndothelium, VascularGenetic Association Studies

Sustainable Development Goals

SDG 3: 3. Good health

Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican

FAIR Checklist

Authors (30)

Funding (20 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)