Multi-omic comparison of Alzheimer’s variants in human ESC–derived microglia reveals convergence at APOE is a dataset published in The Journal of Experimental Medicine (2020). On theSindex it has a DataRank of 2.0, placing it in the top 10.8% of the data-sharing corpus. It has been cited 73 times, with 68 citing works in its 1-hop citation network. Its calibrated FAIR score is 46/100.
Ranks in the top 11% for downstream scientific impact
Linked data & code
DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Full FAIR picture · advisory
The headline score is computed from the scored criteria — the fact-shaped checks (a repository, an accession, a licence) that two independent models agree on. The advisory criteria below are real FAIR guidance but rest on judgment calls that models read differently, so they inform without moving the number.
“GSE153658”
The paper provides a GEO accession number, which is a persistent identifier scheme. [majority verdict 'yes' (4/5 passes agreed)]
RDA-F1-01D — FAIR Data Maturity Model: 'Data is identified by a persistent identifier' (priorit · RDA-F1-02D — FAIR Data Maturity Model: 'Data is identified by a globally unique identifier' · FsF-F1-02D — F-UJI/FAIRsFAIR: 'Data is assigned a persistent identifier'
“Gene Expression Omnibus”
The paper names a proper noun repository (GEO) as the holder. [majority verdict 'yes' (4/5 passes agreed)]
RDA-F4-01M — FAIR Data Maturity Model: metadata is offered so it can be harvested and indexed ( · NIH DMS Policy Element 4 (NOT-OD-21-014) — name the repository where data will be archived · NSTC Desirable Characteristics of Data Repositories (2022) — 'Long-Term Sustainability', 'Reten
“All sequencing data acquired in this study have been deposited in the Gene Expression Omnibus under accession number GSE153658.”— not found in the paper; verdict downgraded
The dataset identifiers appear only in the body text, not in the reference list. [downgraded to 'no' — no verifiable quote from the paper] [majority verdict 'no' (3/5 passes agreed)]
FORCE11 Joint Declaration of Data Citation Principles (2014) — data should be cited as a first- · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes · FsF-F3-01M — F-UJI: 'Metadata includes the identifier of the data it describes'
Advisory · not in the published score
“All sequencing data acquired in this study have been deposited in the Gene Expression Omnibus under accession number GSE153658. Proteomics data included in this study have been deposited in the ProteomeXchange database under accession number PXD020240.”— not found in the paper; verdict downgraded
The statement points to a repository record with accessions, fitting Colavizza category 3. [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (3/5 passes agreed)]
Colavizza, Hrynaszkiewicz, Staden, Whitaker & McGillivray (2020), 'The citation advantage of li · Springer Nature research data policy — Data Availability Statements: standard statement templat · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes
“we curate a comprehensive atlas comprising ATAC-seq, ChIP-seq, RNA-seq, and proteomics datasets”— not found in the paper; verdict downgraded
The dataset content is described in a sentence, not in an itemised inventory. [downgraded to 'no' — no verifiable quote from the paper] [majority verdict 'no' (4/5 passes agreed)]
RDA-F2-01M — 'Rich metadata is provided to allow discovery' (priority Essential) · FsF-F2-01M — F-UJI: 'Metadata includes descriptive core elements to support data findability' · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data'
“All sequencing data acquired in this study have been deposited in the Gene Expression Omnibus under accession number GSE153658.”— not found in the paper; verdict downgraded
The data are deposited in public repositories with no stated precondition. [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (3/5 passes agreed)]
RDA-A1.1-01D — 'Data is accessible through a free access protocol' · FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · NSTC Desirable Characteristics of Data Repositories (2022) — 'Free and Easy Access'
Advisory · not in the published score
“All sequencing data acquired in this study have been deposited in the Gene Expression Omnibus under accession number GSE153658.”— not found in the paper; verdict downgraded
The paper states the data are deposited in public repositories, which implies open access, but does not use an explicit access-level label like 'open access'. [downgraded to 'no' — no verifiable quote from the paper] [majority verdict 'no' (3/5 passes agreed)]
FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · RDA-A1-01M — metadata contains information to enable the user to get access to the data · COAR Controlled Vocabularies — Access Rights v1.0 (open / embargoed / restricted / metadata-onl
The data are not sensitive or human-subject, and no gatekeeper is named.
NIH Genomic Data Sharing Policy (NOT-OD-14-124) — controlled-access via a Data Access Committee · RDA-A1.2-01D — 'Data is accessible through an access protocol that supports authentication and · NIH DMS Policy Element 5 (NOT-OD-21-014) — Access, Distribution, or Reuse Considerations (conse
No persistence commitment or availability timing is stated beyond the deposit statement.
NIH DMS Plan Element 4 (NOT-OD-21-014) — Data Preservation, Access, and Associated Timelines · NSTC Desirable Characteristics (2022), Organizational Infrastructure: 'Retention Policy' · RDA-A2-01M — 'Metadata is guaranteed to remain available after data is no longer available'
No file format token is named for the deposited data.
FsF-R1.3-02D — F-UJI: 'Data is available in a file format recommended by the target research co · RDA-R1.3-02D — data is expressed in a machine-understandable community standard · RDA-I1-01D — data uses a knowledge representation expressed in a standardised format
Advisory · not in the published score
The paper does not explicitly name a data or metadata community standard (e.g., MIAME, MINSEQE, BIDS) for the deposited data; it uses GO and KEGG for analysis but not as a standard for the data itself. [majority verdict 'no' (3/5 passes agreed)]
RDA-R1.3-01M — 'Metadata complies with a community standard' (priority Essential) · RDA-R1.3-01D — 'Data complies with a community standard' · RDA-I2-01M — '(Meta)data use vocabularies that follow FAIR principles'
“GSE117829”
The paper references an external dataset identifier (GSE117829) from other studies. [majority verdict 'yes' (4/5 passes agreed)]
RDA-I3-01M — '(meta)data include references to other (meta)data' · RDA-I3-03M — 'metadata includes qualified references to other metadata' · FsF-I3-01M — F-UJI: 'Metadata includes links between the data and its related entities'
The paper only states a license for the article, not for the data itself.
RDA-R1.1-01M — 'Metadata includes information about the licence under which the data can be reu · RDA-R1.1-02M — 'Metadata refers to a standard reuse licence' · RDA-R1.1-03M — 'Metadata refers to a machine-understandable reuse licence'
No version token or date is provided for the dataset.
DataCite Metadata Schema 4.6 — the 'Version' property · RDA-R1.2-01M — provenance information (which version was used is provenance) · NSTC Desirable Characteristics of Data Repositories (2022) — 'Provenance', 'Retention Policy'
No code deposition or locator is mentioned.
NIH DMS Policy Element 2 (NOT-OD-21-014) — 'Related Tools, Software and/or Code' · FAIR4RS Principles v1.0 (Chue Hong et al., 2022; RDA/FORCE11/ReSA) — FAIR Principles for Resear · FORCE11 Software Citation Principles (Smith, Katz & Niemeyer, 2016, PeerJ CS 2:e86)
“R01 AG061875”
The paper lists specific grant numbers from funders.
DataCite Metadata Schema 4.6 — 'FundingReference' property (funderName, funderIdentifier, award · Crossref Funder Registry — canonical funder identifiers for funding metadata · RDA-F2-01M — rich metadata provided to allow discovery (funding is part of the descriptive reco
Advisory · not in the published score
“sequenced with a NextSeq 500/550 High Output v2 kit using single-end reads on a NextSeq 500 platform (Illumina)”
The paper names specific instruments (NextSeq 500, Orbitrap Lumos) and software versions (STAR v2.7, MaxQuant v1.5.5.1) used to produce the data. [majority verdict 'yes' (3/5 passes agreed)]
RDA-R1.2-01M — 'Metadata includes provenance information according to community- specific standa · FsF-R1.2-01M — F-UJI: 'Metadata includes provenance information about data creation or generati · W3C PROV-O (W3C Recommendation, 2013) — the entity/activity/agent model of provenance
No documentation object (README, codebook) is mentioned as accompanying the data. [majority verdict 'no' (4/5 passes agreed)]
RDA-R1-01M — '(Meta)data are richly described with a plurality of accurate and relevant attribu · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data' · NIH DMS Policy Element 3 (NOT-OD-21-014) — Standards (documentation and metadata to accompany t
Calibrated FAIR score — a parallel quality metric, independent of the DataRank citation score. See the full evaluation →
Base Score Contribution
0.646
From this paper's citation signal
Citation Network Contribution
1.3
From 61 citing papers with measurable signal
Ranked by each citer's contribution to N(p) — log1p(Cq) divided by its reference count — out of 68 citers.
National Institutes of Health
Grant: R01 AG061875
National Institutes of Health
Grant: R01 AG056130
National Institutes of Health
Grant: R01 AG044420
National Institutes of Health
Grant: R21 AG059217
National Institutes of Health
Grant: R01 AG038710
National Institutes of Health
Grant: R01 NS046673
National Institutes of Health
Grant: R01 AG056114
National Cancer Institute
Grant: P30CA030199
NIA NIH HHS
Grant: RF1 AG056130
NIA NIH HHS
Grant: P50 AG016573
NIA NIH HHS
Grant: RF1 AG044420
NIA NIH HHS
Grant: RF1 AG048099
NIA NIH HHS
Grant: P30 AG066519
NIA NIH HHS
Grant: RF1 AG056114
NIA NIH HHS
Grant: R01 AG056303
Cure Alzheimer’s Fund
Tanz Family Fund
FWCI
3.55
Citation Percentile
0.9%
Citation Trend
Fields of Study
MeSH Terms
Keywords