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NFAT-dependent and -independent exhaustion circuits program maternal CD8 T cell hypofunction in pregnancy

The Journal of Experimental Medicine(2021)10.1084/jem.20201599Source: DataRank Database

NFAT-dependent and -independent exhaustion circuits program maternal CD8 T cell hypofunction in pregnancy is a research paper published in The Journal of Experimental Medicine (2021). On theSindex it has a DataRank of 0. It has been cited 33 times.

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Open Access33 citations

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Enrichment:Funding (26 grants)Impact (FWCI 1.69)OA: hybridTopics (79)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Rong Xu ORCID,Jean‐Christophe Beltra ORCID,Shin Foong Ngiow ORCID,Jordana B. Cohen ORCID,Rahul Telange ORCID

Live enrichment

PubMed:34882194 PMC:PMC8666877 OpenAlex:https://openalex.org/W4200295200

National Institutes of Health

Grant: AI105343

National Institutes of Health

Grant: AI117950

National Institutes of Health

Grant: AI082630

National Institutes of Health

Grant: AI112521

National Institutes of Health

Grant: AI115712

National Institutes of Health

Grant: AI108545

National Institutes of Health

Grant: CA210944

National Institutes of Health

Grant: K08 AI130365

NIAID NIH HHS

Grant: P01 AI108545

NIAID NIH HHS

Grant: P01 AI112521

NIAID NIH HHS

Grant: R01 AI115712

NIAID NIH HHS

Grant: U19 AI117950

NCI NIH HHS

Grant: P01 CA210944

NIAID NIH HHS

Grant: U19 AI082630

NIAID NIH HHS

Grant: R01 AI105343

National Institutes of Health

Grant: 5R01AI115712-02

Testing the role of BATF as a pioneer transcription factor in effector T cells

National Institutes of Health

Grant: 2U19AI082630-06

Reversal of Immune Failure with Viral Cure in Chronic HCV Infection

National Institutes of Health

Grant: 5R01AI105343-03

Cellular and transcriptional control of exhausted CD8 T cells lineage dynamics

National Institutes of Health

Grant: 5P01AI112521-05

Mechanisms and Immunological Consequences of Host-Virus Interactions

National Institutes of Health

Grant: 5P01AI108545-08

Synergies among inhibitory receptors in tolerance, cancer & antiviral immunity

National Institutes of Health

Grant: 5K08AI130365-05

Pregnancy-induced T cell exhaustion: an opportunity to reduce immunosuppression

National Institutes of Health

Grant: 5U19AI117950-02

Engineering T cells to Provide Durable Control of HIV-1 Replication

American Surgical Association Foundation

Parker Institute for Cancer Immunotherapy

Harrison Department of Surgical Research

Stand Up To Cancer

FWCI

1.69

Citation Percentile

0.8%

Citation Trend

2022

2023

2024

2025

2026

hybridLicense: cc-by

journalhttps://doi.org/10.1084/jem.20201599

publisherhttps://doi.org/10.1084/jem.20201599

publisherhttps://rupress.org/jem/article-pdf/doi/10.1084/jem.20201599/1821417/jem_20201599.pdf

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34882194

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8666877

Fields of Study

Immune Cell Function and InteractionReproductive System and PregnancyT-cell and B-cell ImmunologyAdoptive TransferAnimalsAntigensCD8-Positive T-LymphocytesChlorocebus aethiopsFemaleGene Expression ProfilingHomeodomain ProteinsHumansKaplan-Meier EstimateLymphocyte ActivationLymphocytic ChoriomeningitisLymphocytic choriomeningitis virusMice, Inbred C57BLMice, TransgenicNFATC Transcription FactorsPregnancyProgrammed Cell Death 1 ReceptorSkin TransplantationSpleenVero CellsMice

MeSH Terms

AnimalsAntigensChlorocebus aethiopsFemaleHumansLymphocyte ActivationLymphocytic ChoriomeningitisLymphocytic choriomeningitis virusMice, Inbred C57BLMice, TransgenicPregnancySpleenVero CellsSkin TransplantationHomeodomain ProteinsCD8-Positive T-LymphocytesAdoptive TransferGene Expression ProfilingNFATC Transcription FactorsMiceKaplan-Meier EstimateProgrammed Cell Death 1 Receptor

Keywords

NFATCD8PregnancyContext (archaeology)ImmunologyBiologyCytotoxic T cellT cellImmune systemTranscription factorGeneticsIn vitroHomeodomain ProteinsNFATC Transcription FactorsGene Expression ProfilingProgrammed Cell Death 1 ReceptorMice, TransgenicKaplan-Meier EstimateSkin TransplantationCD8-Positive T-LymphocytesLymphocytic ChoriomeningitisLymphocyte ActivationAdoptive TransferArticleMice, Inbred C57BLChlorocebus aethiopsAnimalsHumansLymphocytic choriomeningitis virusFemaleAntigensSpleen

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

NFAT-dependent and -independent exhaustion circuits program maternal CD8 T cell hypofunction in pregnancy

FAIR Checklist

Authors (10)

Funding (26 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)