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Suppressive effects of the obese tumor microenvironment on CD8 T cell infiltration and effector function

The Journal of Experimental Medicine(2022)10.1084/jem.20210042Source: DataRank Database

Suppressive effects of the obese tumor microenvironment on CD8 T cell infiltration and effector function is a research paper published in The Journal of Experimental Medicine (2022). On theSindex it has a DataRank of 0.680. It has been cited 92 times.

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0.680DataRank · unranked

Scored on demand from live citation data

Open Access92 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (18 grants)OA: hybridTopics (34)IDs (PubMed, PMC)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.680

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

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Authors (19)

Hannah Prendeville ORCID,Mathilde Raverdeau ORCID,Mieszko M. Wilk ORCID,Róisín M. Loftus ORCID,Aaron Douglas ORCID

Live enrichment

PubMed:35103755 PMC:PMC8932531

Irish Research Council

Grant: GOIPD/2018/602

Science Foundation Ireland

Grant: 3865

European Research Council

Grant: StG_679173

European Research Council

Grant: R01 AI134861

National Institutes of Health

Grant: DK123095

National Institutes of Health

Grant: S10 OD020100

Science Foundation Ireland Precision Oncology Ireland

Grant: 18/SPP/3522

Precision Oncology Ireland

European Research Council

Grant: 679173

Targeting iNKT cell and adipocyte crosstalk for control of metabolism and body weight

NIDDK NIH HHS

Grant: R01 DK123095

National Institutes of Health

Grant: 1S10OD020100-01

Comprehensive Lab Animal Monitor System (CLAMS) for the Study of Mouse Metabolism

Irish Research Council

Grant: unidentified

unidentified

National Institutes of Health

Grant: 5R01DK123095-04

Defining mechanisms of succinate regulation over adipose tissue thermogenesis

National Institutes of Health

Grant: 5R01AI134861-02

Immunometabolic and epigenetic effects of obesity on innate immune surveillance in cancer

Lavine Family Fund

Claudia Adams Barr Program

UCD Clinical Research Centre

Pew Charitable Trusts

Cancer Research Institute

hybridLicense: cc-by

publisherhttps://rupress.org/jem/article-pdf/219/3/e20210042/1429154/jem_20210042.pdf

publisherhttps://rupress.org/jem/article-pdf/doi/10.1084/jem.20210042/1767724/jem_20210042.pdf

repositoryhttps://ruj.uj.edu.pl/xmlui/handle/item/312285

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8932531

Europe_PMChttps://europepmc.org/articles/PMC8932531

Fields of Study

03 medical and health sciences0302 clinical medicine

MeSH Terms

CD8-Positive T-LymphocytesLymphocytes, Tumor-InfiltratingAnimalsMiceMice, ObeseNeoplasmsObesityDisease Models, AnimalAmino AcidsLymphocyte CountImmunotherapyTumor MicroenvironmentDiet, High-Fat

Keywords

innate immunity and inflammation610Mice, ObeseCD8-Positive T-LymphocytesDiet, High-FatArticleDisease Models, AnimalMiceLymphocytes, Tumor-InfiltratingNeoplasms616Tumor MicroenvironmentAnimalstumor immunologyImmunotherapyLymphocyte CountObesityAmino Acidsmetabolism

Sustainable Development Goals

SDG 2: 2. Zero hungerSDG 3: 3. Good health