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Safety of Intravenous Administration of an AAV8 Vector Coding for an Oxidation-Resistant Human α1-Antitrypsin for the Treatment of α1-Antitrypsin Deficiency

Human Gene Therapy(2023)10.1089/hum.2022.192Source: DataRank Database

Safety of Intravenous Administration of an AAV8 Vector Coding for an Oxidation-Resistant Human α1-Antitrypsin for the Treatment of α1-Antitrypsin Deficiency is a research paper published in Human Gene Therapy (2023). On theSindex it has a DataRank of 0. It has been cited 9 times.

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Open Access9 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (2 grants)Impact (FWCI 1.97)OA: greenTopics (28)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (13)

Bishnu P. De,Alessandria Greco,Nicholas Gorman,Vikrum Kooner,Alvin Chen ORCID

Live enrichment

PubMed:36606685 PMC:PMC9963503 OpenAlex:https://openalex.org/W4313651209

NHLBI NIH HHS

Grant: R42 HL140670

NCI NIH HHS

Grant: P30 CA008748

FWCI

1.97

Citation Percentile

0.9%

Citation Trend

2023

2024

2025

2026

greenLicense: https://www.liebertpub.com/nv/resources-tools/text-and-data-mining-policy/121/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC9963503/pdf/hum.2022.192.pdf

publisherhttps://www.liebertpub.com/doi/full-xml/10.1089/hum.2022.192

publisherhttps://www.liebertpub.com/doi/pdf/10.1089/hum.2022.192

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9963503

Fields of Study

Protease and Inhibitor MechanismsPeptidase Inhibition and AnalysisAntimicrobial Peptides and Activities

MeSH Terms

alpha 1-AntitrypsinAnimalsAntibodiesHumansLungPulmonary Emphysemaalpha 1-Antitrypsin DeficiencyMiceAdministration, Intravenous

Keywords

ProteasesOxidative stressPharmacologyImmunogenicityBiologyImmunologyAntibodyMedicineEnzymeBiochemistryΑ1-antitrypsin DeficiencySafety StudyAav Gene TherapyToxicology StudyInd-enabling StudyOxidation-resistant Α1-antitrypsin

Sustainable Development Goals

SDG 0: Good health and well-being