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Pharmacological Profile and Ocular Hypotensive Effects of Cromakalim Prodrug 1, a Novel ATP-Sensitive Potassium Channel Opener, in Normotensive Dogs and Nonhuman Primates

Journal of Ocular Pharmacology and Therapeutics(2021)10.1089/jop.2020.0137Source: DataRank Database

Pharmacological Profile and Ocular Hypotensive Effects of Cromakalim Prodrug 1, a Novel ATP-Sensitive Potassium Channel Opener, in Normotensive Dogs and Nonhuman Primates is a research paper published in Journal of Ocular Pharmacology and Therapeutics (2021). On theSindex it has a DataRank of 0. It has been cited 14 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access14 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 1.80)OA: greenTopics (41)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Rachel A. Kudgus ORCID,Bradley H. Holman,Tommy A. Rinkoski ORCID,Cheryl R. Hann,Cindy K. Bahler

Live enrichment

PubMed:33784195 PMC:PMC8215408 OpenAlex:https://openalex.org/W3140354830

NIH HHS

Grant: P40 OD010965

NEI NIH HHS

Grant: R01 EY021727

NCATS NIH HHS

Grant: UL1 TR001420

FWCI

1.80

Citation Percentile

0.8%

Citation Trend

2022

2023

2025

2026

green

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8215408

journalhttps://doi.org/10.1089/jop.2020.0137

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33784195

Fields of Study

Glaucoma and retinal disordersReceptor Mechanisms and SignalingInflammatory mediators and NSAID effects

MeSH Terms

Administration, TopicalAnimalsAntihypertensive AgentsAutopsyBlood PressureChlorocebus aethiopsDogsDose-Response Relationship, DrugFemaleHalf-LifeIntraocular PressurePrimatesProdrugsArea Under CurveCromakalimModels, AnimalKATP ChannelsAdministration, Ophthalmic

Keywords

CromakalimCmaxPharmacokineticsMedicineBlood pressurePotassium channel openerIntraocular pressureAnesthesiaProdrugHypokalemiaPharmacologyEndocrinologyPotassium channelSurgeryDogsNonhuman primatesIopLevcromakalimCklp1Katp Channel Openers