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Inhibition of ALK-Signaling Overcomes STRN-ALK-Induced Downregulation of the Sodium Iodine Symporter and Restores Radioiodine Uptake in Thyroid Cells

Thyroid(2022)10.1089/thy.2022.0533Source: DataRank Database

Inhibition of ALK-Signaling Overcomes STRN-ALK-Induced Downregulation of the Sodium Iodine Symporter and Restores Radioiodine Uptake in Thyroid Cells is a research paper published in Thyroid (2022). On theSindex it has a DataRank of 0. It has been cited 22 times.

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Open Access22 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (1 grants)Impact (FWCI 2.53)OA: greenTopics (41)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Vincenzo Condello ORCID,Saurabh S. Divakaran ORCID,Yuri E. Nikiforov ORCID,Alyaksandr V. Nikitski ORCID

Live enrichment

PubMed:36585857 PMC:PMC10122237 OpenAlex:https://openalex.org/W4313323884

NCI NIH HHS

Grant: R01 CA181150

FWCI

2.53

Citation Percentile

0.9%

Citation Trend

2023

2024

2025

2026

greenLicense: https://journals.sagepub.com/page/policies/text-and-data-mining-license

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10122237/pdf/thy.2022.0533.pdf

publisherhttps://journals.sagepub.com/doi/full-xml/10.1089/thy.2022.0533

publisherhttps://journals.sagepub.com/doi/pdf/10.1089/thy.2022.0533

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/10122237

Fields of Study

Thyroid Cancer Diagnosis and TreatmentCancer-related Molecular PathwaysLung Cancer Treatments and Mutations

MeSH Terms

CrizotinibCalmodulin-Binding ProteinsHumansIodine RadioisotopesMembrane ProteinsNerve Tissue ProteinsNitrilesPyrazolesPyrimidinesSodiumSulfonesThyroid NeoplasmsDown-RegulationPhosphatidylinositol 3-KinasesReceptor Protein-Tyrosine KinasesMonocarboxylic Acid TransportersSymporters

Keywords

Cancer researchThyroid cancerAnaplastic thyroid cancerCrizotinibThyroidSymporterDownregulation and upregulationSodium-iodide symporterCarcinogenesisAnaplastic lymphoma kinasePI3K/AKT/mTOR pathwayMedicineChemistryCancerInternal medicineSignal transductionLung cancerBiochemistryRedifferentiationSodium Iodine SymporterStrn-alk

Sustainable Development Goals

SDG 0: Good health and well-being