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Predicting differentially methylated cytosines in TET and DNMT3 knockout mutants via a large language model

Briefings in Bioinformatics(2025)10.1093/bib/bbaf092Source: DataRank Database

Predicting differentially methylated cytosines in TET and DNMT3 knockout mutants via a large language model is a research paper published in Briefings in Bioinformatics (2025). On theSindex it has a DataRank of 0.

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Enrichment:Funding (4 grants)Impact (FWCI 0.00)OA: goldTopics (82)IDs (PubMed, PMC, OpenAlex)

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Open Access

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Authors (1)

Stefano Lonardi ORCID

Live enrichment

PubMed:40079264 PMC:PMC11904404 OpenAlex:https://openalex.org/W4408387353

US National Institutes of Health

Grant: 1R01AI169543-01

Rapid response for pandemics: single cell sequencing and deep learning to predict antibody sequences against an emerging antigen

US National Science Foundation

Grant: 2225878

Collaborative Research: Data-driven engineering of the thermotolerant yeast Kluyveromyces marxianus

US National Science Foundation

Grant: 244456

NIAID NIH HHS

Grant: R01 AI169543

FWCI

0.00

Citation Percentile

0.0%

goldLicense: cc-by-nc

journalhttps://academic.oup.com/bib/article-pdf/26/2/bbaf092/62397927/bbaf092.pdf

publisherhttps://academic.oup.com/bib/article-pdf/26/2/bbaf092/62397927/bbaf092.pdf

journalhttps://doi.org/10.1093/bib/bbaf092

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40079264

repositoryhttps://escholarship.org/uc/item/2hd4w7c4

Fields of Study

Epigenetics and DNA MethylationCancer-related gene regulationRNA modifications and cancer0206 medical engineering02 engineering and technologyDNA MethylationDNA (Cytosine-5-)-MethyltransferasesAnimalsMiceHumansMachine LearningCytosineMutationDNA Methyltransferase 3AEmbryonic Stem CellsDNA Methyltransferase 3BDNA-Binding ProteinsGene Knockout TechniquesProto-Oncogene ProteinsLarge Language Models

MeSH Terms

Machine LearningDNA Methyltransferase 3ADNA Methyltransferase 3BLarge Language ModelsAnimalsCytosineDNA (Cytosine-5-)-MethyltransferasesDNA-Binding ProteinsHumansMutationProto-Oncogene ProteinsDNA MethylationEpigenesis, GeneticDioxygenasesMiceEmbryonic Stem CellsGene Knockout Techniques

Keywords

DNA methylationEpigeneticsComputational biologyBiologyMethylationEnhancerGeneticsDNAGeneTranscription factorGene expressionDnmt3TetCytosine MethylationBertLarge Language ModelDNA Methyltransferase 3BBioinformaticsBioinformatics and Computational BiologyStem Cell Research - Embryonic - Non-HumanArticleDioxygenasesDNA Methyltransferase 3AMachine LearningMiceCytosineGene Knockout TechniquesLarge Language ModelsGeneticProto-Oncogene ProteinsAnimalsHumansDNA (Cytosine-5-)-MethyltransferasesOther Information and Computing SciencesEmbryonic Stem CellsHuman GenomeComputation Theory and MathematicsBiological SciencesStem Cell ResearchDNA-Binding ProteinsBiochemistry and cell biologyMutationProblem Solving ProtocolGeneric health relevanceEpigenesis