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The genetic architecture of human complex phenotypes is modulated by linkage disequilibrium and heterozygosity

Genetics(2021)10.1093/genetics/iyaa046Source: DataRank Database

The genetic architecture of human complex phenotypes is modulated by linkage disequilibrium and heterozygosity is a research paper published in Genetics (2021). On theSindex it has a DataRank of 0. It has been cited 17 times.

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Enrichment:Funding (7 grants)OA: hybridTopics (34)IDs (PubMed, PMC)Annotations (1)

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Authors (8)

Oleksandr Frei ORCID,Rahul S. Desikan ORCID,Chun-Chieh Fan,Alexey Shadrin ORCID,Olav B. Smeland ORCID

Live enrichment

PubMed:33789345 PMC:PMC8045737

Research Council of Norway

Grant: 262656

Identifying rare variants in schizophrenia with long range phasing of Norwegian population

Research Council of Norway

Grant: 248984

Research Council of Norway

Grant: 248778

Identifying the missing heritability of complex diseases leveraging biobanks, registries and novel analytical tools in psychiatric disorders

Research Council of Norway

Grant: 223273

NORMENT; Norwegian Centre for Mental Disorders Research

NIH

Grant: U24DA041123

National Institutes of Health

Grant: 2U24DA041123-06

ABCD-USA Consortium: Data Analysis, Informatics and Resource Center

KG Jebsen Stiftelsen

hybridLicense: OUP Standard Publication Reuse

publisherhttp://academic.oup.com/genetics/advance-article-pdf/doi/10.1093/genetics/iyaa046/36270138/iyaa046.pdf

publisherhttp://academic.oup.com/genetics/article-pdf/217/3/iyaa046/40416089/iyaa046.pdf

https://doi.org/10.1093/genetics/iyaa046

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045737

https://pubmed.ncbi.nlm.nih.gov/33789345

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

HumansHeterozygoteMultifactorial InheritanceLinkage DisequilibriumPhenotypePolymorphism, Single NucleotideModels, Genetic

Keywords

HeritabilityNatural selectionlinkage disequilibriumEffect SizeMinor Allele FrequencyPolygenicityHeterozygoteMultifactorial Inheritance610Polymorphism, Single NucleotideGeneticModelsGenetics2.1 Biological and endogenous factorsHumansPolymorphismModels, GeneticHuman GenomeSingle NucleotideBiological SciencesPhenotypeBiochemistry and cell biologyGeneric health relevanceDevelopmental Biology