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Functional classification of GNAI1 disorder variants in Caenorhabditis elegans uncovers conserved and cell-specific mechanisms of dysfunction

Genetics(2025)10.1093/genetics/iyaf216Source: DataRank Database

Functional classification of GNAI1 disorder variants in Caenorhabditis elegans uncovers conserved and cell-specific mechanisms of dysfunction is a research paper published in Genetics (2025). On theSindex it has a DataRank of 0.

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Enrichment:Funding (4 grants)Impact (FWCI 0.48)OA: hybridTopics (25)IDs (PubMed, PMC, OpenAlex)Annotations (3)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Eric Peet,Logan Morrione,Sarah M. Durant ORCID,Maxwell D. Seager ORCID,Madison Rennie

Live enrichment

PubMed:41052774 PMC:PMC12693566 OpenAlex:https://openalex.org/W4414867018

National Institutes of Health

Grant: R35 GM155316

NIH HHS

Grant: P40 OD010440

Charles H. Hood Foundation

Child Health Research Award

FWCI

0.48

Citation Percentile

0.6%

Citation Trend

2026

hybridLicense: cc-by

journalhttps://academic.oup.com/genetics/advance-article-pdf/doi/10.1093/genetics/iyaf216/64522133/iyaf216.pdf

publisherhttps://academic.oup.com/genetics/advance-article-pdf/doi/10.1093/genetics/iyaf216/64522133/iyaf216.pdf

publisherhttps://academic.oup.com/genetics/article-pdf/231/4/iyaf216/64522133/iyaf216.pdf

journalhttps://doi.org/10.1093/genetics/iyaf216

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41052774

Fields of Study

Genetics, Aging, and Longevity in Model OrganismsBirth, Development, and Health

MeSH Terms

AnimalsCiliaHumansMutationNeuronsPhenotypeCaenorhabditis elegansGTP-Binding Protein alpha Subunits, Gi-GoCaenorhabditis elegans ProteinsCRISPR-Cas Systems

Keywords

Caenorhabditis elegansCiliogenesisCiliumFunction (biology)MutationHuman geneticsConserved sequenceGeneCiliaNeurodevelopmental DisordersGnai1Gα ProteinsOdr-3

Functional classification of GNAI1 disorder variants in Caenorhabditis elegans uncovers conserved and cell-specific mechanisms of dysfunction

FAIR Checklist

Authors (7)

Funding (4 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)