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Prevention of premature death and seizures in a Depdc5 mouse epilepsy model through inhibition of mTORC1

Human Molecular Genetics(2020)10.1093/hmg/ddaa068Source: DataRank Database

Prevention of premature death and seizures in a Depdc5 mouse epilepsy model through inhibition of mTORC1 is a research paper published in Human Molecular Genetics (2020). On theSindex it has a DataRank of 0. It has been cited 44 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access44 citations

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Linked data & code

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 1.94)OA: hybridTopics (67)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Brittany Short,Chengwen Zhou ORCID,Robert P. Carson ORCID,Lindsay K. Klofas ORCID

Live enrichment

PubMed:32280987 PMC:PMC7254848 OpenAlex:https://openalex.org/W3016010963

National Institutes of Health

Grant: K08 NS083710

National Institute of General Medical Sciences

Grant: T32GM007347

National Institutes of Health

Grant: 5T32GM007347-08

MEDICAL SCIENTIST TRAINING PROGRAM

National Institutes of Health

Grant: 6K08NS083710-05

mTOR modulation of myelination

FWCI

1.94

Citation Percentile

0.9%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

hybridLicense: cc-by

journalhttps://academic.oup.com/hmg/article-pdf/29/8/1365/33318790/ddaa068.pdf

publisherhttps://academic.oup.com/hmg/article-pdf/29/8/1365/33318790/ddaa068.pdf

publisherhttp://academic.oup.com/hmg/advance-article-pdf/doi/10.1093/hmg/ddaa068/33163027/ddaa068.pdf

publisherhttp://academic.oup.com/hmg/article-pdf/29/8/1365/33318790/ddaa068.pdf

journalhttps://doi.org/10.1093/hmg/ddaa068

Fields of Study

Mitochondrial Function and PathologyNeuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders03 medical and health sciences0302 clinical medicineAnimalsAstrocytesDisease Models, AnimalEpilepsyGABAergic NeuronsGTPase-Activating ProteinsHomeodomain ProteinsHumansMechanistic Target of Rapamycin Complex 1MiceMice, KnockoutMortality, PrematureMutationPhenotypeSeizuresSignal TransductionTranscription FactorsEmpty Spiracles Homeobox Proteins

MeSH Terms

Mechanistic Target of Rapamycin Complex 1Empty Spiracles Homeobox ProteinsAnimalsAstrocytesDisease Models, AnimalEpilepsyHumansMutationPhenotypeSeizuresTranscription FactorsSignal TransductionMice, KnockoutHomeodomain ProteinsGTPase-Activating ProteinsMiceGABAergic NeuronsMortality, Premature

Keywords

EpilepsyEpileptogenesismTORC1NeuroscienceBiologyExcitatory postsynaptic potentialInhibitory postsynaptic potentialPI3K/AKT/mTOR pathwayCell biologySignal transductionHomeodomain ProteinsMice, KnockoutMortality, PrematureGTPase-Activating ProteinsMechanistic Target of Rapamycin Complex 1Empty Spiracles Homeobox ProteinsDisease Models, AnimalMicePhenotypeSeizuresAstrocytesMutationAnimalsHumansGABAergic NeuronsTranscription Factors

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being