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Reversing lysosome-ribosome circuit dysregulation mitigates C9FTD/ALS neurodegeneration and behaviors

Human Molecular Genetics(2022)10.1093/hmg/ddac271Source: DataRank Database

Reversing lysosome-ribosome circuit dysregulation mitigates C9FTD/ALS neurodegeneration and behaviors is a research paper published in Human Molecular Genetics (2022). On theSindex it has a DataRank of 0. It has been cited 2 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access2 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 0.24)OA: hybridTopics (49)IDs (PubMed, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Liang Chen ORCID,Jing Wang ORCID,Qing Chang ORCID,Yuan Wang ORCID,Wei Zhang ORCID

Live enrichment

PubMed:36322143 OpenAlex:https://openalex.org/W4307967840

National Institutes of Health

Grant: R21AG070681

National Institutes of Health

Grant: R21AG075665

National Institutes of Health

Grant: R01DE030901

National Institutes of Health

Grant: 5R01DE030901-03

Mechanisms and rescue of craniosynostosis associated with gene-environment interaction

National Institutes of Health

Grant: 1R21AG075665-01

Neurovascular functions of a small RNA Snord118-mediated ribosome biogenesis

National Institutes of Health

Grant: 1R21AG070681-01A1

Selective neurovascular regulation by a vascular dementia-related noncoding RNA Snord118

FWCI

0.24

Citation Percentile

0.6%

Citation Trend

2023

2025

hybridLicense: public-domain

journalhttps://academic.oup.com/hmg/article-pdf/32/8/1252/49778408/ddac271.pdf

publisherhttps://academic.oup.com/hmg/article-pdf/32/8/1252/49778408/ddac271.pdf

publisherhttps://academic.oup.com/hmg/advance-article-pdf/doi/10.1093/hmg/ddac271/47765385/ddac271.pdf

journalhttps://doi.org/10.1093/hmg/ddac271

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36322143

Fields of Study

Amyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders ResearchMitochondrial Function and Pathology0301 basic medicine0303 health sciences03 medical and health sciencesAnimalsMiceAmyotrophic Lateral SclerosisFrontotemporal DementiaC9orf72 ProteinRibosomesLysosomesDNA Repeat ExpansionCarrier ProteinsFrontotemporal Dementia With Motor Neuron Disease

MeSH Terms

C9orf72 ProteinAmyotrophic Lateral SclerosisAnimalsCarrier ProteinsLysosomesRibosomesDNA Repeat ExpansionMiceFrontotemporal Dementia

Keywords

C9orf72NeurodegenerationBiologyRibosome biogenesisTrinucleotide repeat expansionCell biologyHaploinsufficiencyNeuroscienceGeneticsRNARibosomePhenotypeGeneMedicineDiseaseMiceDNA Repeat ExpansionC9orf72 ProteinFrontotemporal DementiaAmyotrophic Lateral SclerosisAnimalsLysosomesCarrier ProteinsRibosomes

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being