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The expression of congenital Shoc2 variants induces AKT-dependent crosstalk activation of the ERK1/2 pathway

Human Molecular Genetics(2024)10.1093/hmg/ddae100Source: DataRank Database

The expression of congenital Shoc2 variants induces AKT-dependent crosstalk activation of the ERK1/2 pathway is a research paper published in Human Molecular Genetics (2024). On theSindex it has a DataRank of 0.

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Enrichment:Funding (3 grants)Impact (FWCI 0.00)OA: greenTopics (43)IDs (PubMed, PMC, OpenAlex)Annotations (1)

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Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Lina Abdelmoti,Tianyan Gao ORCID,Emilia Galperin ORCID,Patricia G. Wilson

Live enrichment

PubMed:38881369 PMC:PMC11373329 OpenAlex:https://openalex.org/W4399749523

National Institute of General Medical Sciences

Grant: R35GM136295

National Institute of General Medical Sciences

Grant: 1S10OD025033-01

NIH HHS

Grant: S10 OD025033

FWCI

0.00

Citation Percentile

0.1%

greenLicense: https://academic.oup.com/pages/standard-publication-reuse-rights

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11373329/pdf/ddae100.pdf

publisherhttps://academic.oup.com/hmg/article-pdf/33/18/1592/59001062/ddae100.pdf

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11373329

journalhttps://doi.org/10.1093/hmg/ddae100

Fields of Study

Protein Tyrosine PhosphatasesGalectins and Cancer BiologyPI3K/AKT/mTOR signaling in cancerHumansErbB ReceptorsProto-Oncogene Proteins c-aktMAP Kinase Signaling SystemPhosphorylationNoonan SyndromeSignal TransductionSon of Sevenless ProteinsMutationHEK293 CellsIntracellular Signaling Peptides and ProteinsMitogen-Activated Protein Kinase 3

MeSH Terms

HumansMutationNoonan SyndromePhosphorylationSignal TransductionSon of Sevenless ProteinsMAP Kinase Signaling SystemIntracellular Signaling Peptides and ProteinsMitogen-Activated Protein Kinase 3Proto-Oncogene Proteins c-aktHEK293 CellsErbB Receptors

Keywords

BiologyPhosphorylationProtein kinase BSignal transductionCell biologyCancer researchMutantGeneticsGeneEGFRScaffold proteinERK1/2AKTPakShoc2Noonan-like Syndrome With Loose Anagen Hair (Nslh)