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Combination adjuvant improves influenza virus immunity by downregulation of immune homeostasis genes in lymphocytes

ImmunoHorizons(2025)10.1093/immhor/vlae007Source: DataRank Database

Combination adjuvant improves influenza virus immunity by downregulation of immune homeostasis genes in lymphocytes is a research paper published in ImmunoHorizons (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (23 grants)Impact (FWCI 2.08)OA: goldTopics (61)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

Jenny E. Hernandez‐Davies,Jiin Felgner,Aarti Jain ORCID,Ji Won Hwang ORCID,Erwin Strahsburger ORCID

Live enrichment

PubMed:39849993 PMC:PMC11841980 OpenAlex:https://openalex.org/W4406781875

Molecular Mechanisms of Combination Adjuvants

Grant: U01AI160397

Defense Threat Reduction Agency

Grant: HDTRA-1-18-0036

NIAID

Grant: R01AI168063

National Science Foundation

Grant: DMS1763272

Simons Foundation

Grant: 594598

Comprehensive Cancer Center

Grant: P30CA-062203

UCI Skin Biology Resource Based Center

Grant: P30AR075047

Genomics Research and Technology Hub

Grant: 1S10OD010794-01

PacBio RS Single Molecule, Real-Time (SMRT) DNA Sequencer

Genomics Research and Technology Hub

Grant: 1S10OD021718-01

High-Throughput DNA Sequencer

NIH HHS

Grant: S10 OD021718

NIH HHS

Grant: S10 OD010794

NCI NIH HHS

Grant: P30 CA062203

NIGMS NIH HHS

Grant: T32 GM136624

National Institutes of Health

Grant: 5U01AI160397-02

Defining molecular mechanisms of combination adjuvants: a systems immunology, transcriptomics and imaging approach

National Institutes of Health

Grant: 3P30CA062203-27S1

Clinical Trial Advancement and Development for Sarcomas

National Institutes of Health

Grant: 5P30AR075047-04

Skin Biology Resource-Based Center at UCI

National Institutes of Health

Grant: 5R01AI168063-02

Tissue-Specific Mechanisms of Regulatory T Cells in the CNS during Autoimmune Encephalomyelitis

National Science Foundation

Grant: 1763272

NSF-Simons Center for Multiscale Cell Fate Research

NIH

National Institute of Allergy and Infectious Diseases

National Institutes of Health

Genomics Research and Technology Hub

University of California, Irvine

FWCI

2.08

Citation Percentile

0.9%

Citation Trend

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://academic.oup.com/immunohorizons/article-pdf/9/2/vlae007/61529788/vlae007.pdf

publisherhttps://academic.oup.com/immunohorizons/article-pdf/9/2/vlae007/61529788/vlae007.pdf

journalhttps://doi.org/10.1093/immhor/vlae007

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39849993

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11841980

Fields of Study

Influenza Virus Research StudiesImmune Cell Function and InteractionImmune Response and Inflammation0301 basic medicine03 medical and health sciences

MeSH Terms

Adjuvants, VaccineAdjuvants, ImmunologicAnimalsAntibodies, ViralFemaleHomeostasisInfluenza VaccinesLipid ALymphocytesMice, Inbred BALB COligodeoxyribonucleotidesOrthomyxoviridae InfectionsPolysorbatesSaponinsSqualeneDown-RegulationHemagglutinin Glycoproteins, Influenza VirusMiceInfluenza A Virus, H5N1 SubtypeAntibodies, Neutralizing

Keywords

ImmunogenicityAdjuvantImmune systemCpG OligodeoxynucleotideBiologyAntigenVirologyImmunologyAntibodyHemagglutinin (influenza)GeneGene expressionLymphocytesInfluenzasynergySingle-cell TranscriptomicsCombination AdjuvantSqualeneMice, Inbred BALB CInfluenza A Virus, H5N1 SubtypeDown-RegulationPolysorbatesHemagglutinin Glycoproteins, Influenza VirusSaponinsAntibodies, ViralAntibodies, NeutralizingMiceLipid AAdjuvants, ImmunologicOrthomyxoviridae InfectionsOligodeoxyribonucleotidesInfluenza VaccinesAnimalsHomeostasisFemaleResearch Article

Sustainable Development Goals

SDG 0: Good health and well-being