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CRISPR Correction of the GBA Mutation in Human-Induced Pluripotent Stem Cells Restores Normal Function to Gaucher Macrophages and Increases Their Susceptibility to Mycobacterium tuberculosis

The Journal of Infectious Diseases(2023)10.1093/infdis/jiad141Source: DataRank Database

CRISPR Correction of the GBA Mutation in Human-Induced Pluripotent Stem Cells Restores Normal Function to Gaucher Macrophages and Increases Their Susceptibility to Mycobacterium tuberculosis is a research paper published in The Journal of Infectious Diseases (2023). On theSindex it has a DataRank of 0. It has been cited 9 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access9 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 1.27)OA: bronzeTopics (32)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Amit Kumar ORCID,Stefanie Krug ORCID,Harikrishnan Mohan ORCID,Desirazu N. Rao ORCID,William R. Bishai ORCID

Live enrichment

PubMed:37159513 PMC:PMC10686692 OpenAlex:https://openalex.org/W4376121947

National Institutes of Health

Grant: AI133530

NIAID NIH HHS

Grant: R21 AI133530

CF Foundation

FWCI

1.27

Citation Percentile

0.8%

Citation Trend

2023

2024

2025

2026

bronzeLicense: https://academic.oup.com/pages/standard-publication-reuse-rights

journalhttps://academic.oup.com/jid/advance-article-pdf/doi/10.1093/infdis/jiad141/50502587/jiad141.pdf

publisherhttps://academic.oup.com/jid/advance-article-pdf/doi/10.1093/infdis/jiad141/50502587/jiad141.pdf

publisherhttps://academic.oup.com/jid/article-pdf/228/6/777/53940494/jiad141.pdf

journalhttps://doi.org/10.1093/infdis/jiad141

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37159513

Fields of Study

Lysosomal Storage Disorders ResearchCRISPR and Genetic EngineeringCellular transport and secretion

MeSH Terms

Gaucher DiseaseGlucosylceramidaseHumansMacrophagesMutationMycobacterium tuberculosisInduced Pluripotent Stem CellsClustered Regularly Interspaced Short Palindromic Repeats

Keywords

BiologyInduced pluripotent stem cellGlucocerebrosidaseCRISPRMycobacterium tuberculosisStem cellMacrophageMutationGeneticsMicrobiologyGeneTuberculosisIn vitroEmbryonic stem cellMedicinePathologyGaucher DiseaseHuman-induced Pluripotent Stem Cells (Hipscs)Macrophage MotilityCrispr/cas9 EditingMycobacterium Tuberculosis Uptake And Multiplication

Sustainable Development Goals

SDG 0: Good health and well-being