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Preclinical evaluation of the efficacy and safety of adeno-associated virus 8-tissue-nonspecific alkaline phosphatase-D10 in Alpl-/- and AlplPrx1/Prx1 mouse models for the treatment of early and late-onset hypophosphatasia

Journal of Bone and Mineral Research(2025)10.1093/jbmr/zjaf005Source: DataRank Database

Preclinical evaluation of the efficacy and safety of adeno-associated virus 8-tissue-nonspecific alkaline phosphatase-D10 in Alpl-/- and AlplPrx1/Prx1 mouse models for the treatment of early and late-onset hypophosphatasia is a research paper published in Journal of Bone and Mineral Research (2025). On theSindex it has a DataRank of 0. It has been cited 9 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access9 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)Impact (FWCI 5.44)OA: greenTopics (33)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Cíntia Kazuko Tokuhara ORCID,Fatma F. Mohamed ORCID,Sonoko Narisawa,Elis Janaína Lira dos Santos ORCID,Natalie L. Andras

Live enrichment

PubMed:39799564 OpenAlex:https://openalex.org/W4406292263

National Institutes of Health

Grant: R01 DE12889

National Institutes of Health

Grant: R21 DE031889

National Institutes of Health

Grant: AG0811167

National Institutes of Health

Grant: R01 DE032334

NIDCR NIH HHS

Grant: R01 DE012889

NIA NIH HHS

Grant: P01 AG081167

Endocrine Fellows Foundation

Aruvant Pharmaceuticals

FWCI

5.44

Citation Percentile

1.0%

Citation Trend

2025

2026

greenLicense: https://academic.oup.com/pages/standard-publication-reuse-rights

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12010167/pdf/zjaf005.pdf

publisherhttps://academic.oup.com/jbmr/advance-article-pdf/doi/10.1093/jbmr/zjaf005/61416481/zjaf005.pdf

publisherhttps://academic.oup.com/jbmr/article-pdf/40/4/463/61416481/zjaf005.pdf

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12010167/

Fields of Study

Alkaline Phosphatase Research Studiesthermodynamics and calorimetric analysesBone health and treatmentsAnimalsFemaleMaleMiceAlkaline PhosphataseDependovirusDisease Models, AnimalHypophosphatasiaMice, Knockout

MeSH Terms

DependovirusAlkaline PhosphataseAnimalsDisease Models, AnimalFemaleHypophosphatasiaMaleMice, KnockoutMice

Keywords

HypophosphatasiaMedicineInternal medicineAlkaline phosphataseChemistryBiochemistryEnzymeAAV8-TNAP-D10skeletal mineralizationadult-HPPgene therapyinfantile-HPPinflammation

Sustainable Development Goals

SDG 0: Good health and well-being