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Improvements in hearing loss with bone-targeted enzyme replacement therapy are associated with corrected hypomineralization and osteocyte properties of auditory ossicles in Enpp1-deficient mice

Journal of Bone and Mineral Research(2025)10.1093/jbmr/zjaf082Source: DataRank Database

Improvements in hearing loss with bone-targeted enzyme replacement therapy are associated with corrected hypomineralization and osteocyte properties of auditory ossicles in Enpp1-deficient mice is a research paper published in Journal of Bone and Mineral Research (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 0.89)OA: greenTopics (51)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Shivani Srivastava ORCID,Simon von Kroge ORCID,Paul R. Stabach,Björn Busse ORCID,Keith Weise

Live enrichment

PubMed:40495691 PMC:PMC12406126 OpenAlex:https://openalex.org/W4411192975

National Institutes of Health

Grant: R01AR080416

German Research Foundation

Grant: OH324/2-1

German Research Foundation

Grant: RO 5925/5-1

Deutsche Forschungsgemeinschaft

Grant: unidentified

unidentified

FWCI

0.89

Citation Percentile

0.7%

Citation Trend

2025

greenLicense: OUP Standard Publication Reuse

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12406126/pdf/nihms-2158726.pdf

publisherhttps://academic.oup.com/jbmr/advance-article-pdf/doi/10.1093/jbmr/zjaf082/63467307/zjaf082.pdf

publisherhttps://academic.oup.com/jbmr/article-pdf/40/9/1077/63467307/zjaf082.pdf

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12406126/

Fields of Study

Connective tissue disorders researchBone Metabolism and DiseasesCell Adhesion Molecules Research0303 health sciences03 medical and health sciencesAnimalsPhosphoric Diester HydrolasesPyrophosphatasesHearing LossEnzyme Replacement TherapyMiceOsteocytesMaleEar OssiclesCalcification, PhysiologicMice, Knockout

MeSH Terms

AnimalsCalcification, PhysiologicEar OssiclesMaleOsteocytesPhosphoric Diester HydrolasesPyrophosphatasesMice, KnockoutHearing LossMiceEnzyme Replacement Therapy

Keywords

OsteocyteOssiclesHearing lossMedicineAudiologyAnatomyBiologyMiddle earBiochemistryMineralizationAnimal modelEnpp1Osteocyte LacunaeMaleMice, KnockoutPhosphoric Diester HydrolasesOsteocytesMiceCalcification, PhysiologicAnimalsEnzyme Replacement TherapyPyrophosphatasesResearch ArticleEar Ossicles

Sustainable Development Goals

SDG 0: Good health and well-being