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Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone

JBMR Plus(2024)10.1093/jbmrpl/ziae011Source: DataRank Database

Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone is a research paper published in JBMR Plus (2024). On theSindex it has a DataRank of 0. It has been cited 8 times.

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Open Access8 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (22 grants)OA: goldTopics (13)IDs (PubMed, PMC)Annotations (3)

FAIR Checklist

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Kelly L. Wentworth ORCID,Tania Moody ORCID,Ariane Zamarioli ORCID,Apsara Ram,Gauri Ganesh

Live enrichment

PubMed:38577521 PMC:PMC10994528

National Institutes of Health

Grant: NIDCR R01 DE022032

National Institutes of Health

Grant: NIDCR R21 DE027138

National Institutes of Health

Grant: NIAMS AR056299

NIDCR K08 Career Development Award

Grant: DE028946

NIH Loan Repayment Award

Grant: 1 L30 DE029063-01

University of Pennsylvania Million Dollar Bike Ride

Grant: MDBR-19-111-FD/MAS

UCSF Core Center for Musculoskeletal Biology and Medicine

Grant: NIH P30AR075055

NIAMS NIH HHS

Grant: K08 AR056299

NIDCR NIH HHS

Grant: R21 DE027138

NICHD NIH HHS

Grant: F32 HD091025

NIAMS NIH HHS

Grant: P30 AR075055

NIDCR NIH HHS

Grant: K08 DE028946

NIDCR NIH HHS

Grant: L30 DE029063

NIDCR NIH HHS

Grant: R01 DE022032

National Institutes of Health

Grant: 4R01DE022032-05

Load-mediated Adaptation of the Bone-PDL-Tooth Complex in Vertebrates

National Institutes of Health

Grant: 5R21DE027138-02

Pressure-inducer and Sensor to Map Dynamic Periodontal Mechanobiological Activity

National Institutes of Health

Grant: 1K08DE028946-01

Dissecting the Cellular and Molecular Mechanisms Contributing to Craniofacial Fibrous Dysplasia

National Institutes of Health

Grant: 5P30AR075055-03

Core Center for Musculoskeletal Biology and Medicine (Overall Application)

National Institutes of Health

Grant: 5K08AR056299-06

Regulation of Bone Formation by G-protein Signaling

Kaohsiung Chang Gung Memorial Hospital

University of California Department of Medicine Robert L. Kroc Chair of Rheumatic and Connective Tissue Diseases III

Chang Gung University College of Medicine Doctoral Training Fellowship

goldLicense: CC BY

publisherhttps://academic.oup.com/jbmrplus/advance-article-pdf/doi/10.1093/jbmrpl/ziae011/56321530/ziae011.pdf

publisherhttps://academic.oup.com/jbmrplus/article-pdf/8/5/ziae011/57156168/ziae011.pdf

Europe_PMChttps://europepmc.org/articles/PMC10994528

Europe_PMChttps://europepmc.org/articles/PMC10994528?pdf=render

https://doi.org/10.1093/jbmrpl/ziae011

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

OsteoblastsGpcrTrabecular BoneGnasGsαG-protein Coupled Receptor SignalingWnt Pathway InhibitionFibrous Dysplasia (Fd)Fibrotic Bone DiseaseResearch Article