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NLRC4 deficiency improves host protection during sepsis by regulating macrophage and T-cell responses

The Journal of Immunology(2025)10.1093/jimmun/vkaf272Source: DataRank Database

NLRC4 deficiency improves host protection during sepsis by regulating macrophage and T-cell responses is a research paper published in The Journal of Immunology (2025). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (7 grants)Impact (FWCI 0.00)OA: greenTopics (40)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Laxman Ghimire ORCID,Duane Jeansonne ORCID,Shanshan Cai ORCID,Dinesh Bhattarai ORCID,John Le ORCID

Live enrichment

PubMed:41071588 PMC:PMC12856560 OpenAlex:https://openalex.org/W4415052351

National Institutes of Health

Grant: R01 AI157353

National Institutes of Health

Grant: R01 AI140500

COBRE

Grant: COBRE P20 GM13055-01

predoctoral fellowship

Grant: F31HL-168986

NIGMS NIH HHS

Grant: P20 GM130555

NHLBI NIH HHS

Grant: F31 HL168986

NHLBI NIH HHS

Grant: F31 HL137287

FWCI

0.00

Citation Percentile

0.2%

greenLicense: https://academic.oup.com/pages/standard-publication-reuse-rights

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12856560/

publisherhttps://academic.oup.com/jimmunol/article-pdf/215/1/vkaf272/64613342/vkaf272.pdf

journalhttps://doi.org/10.1093/jimmun/vkaf272

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41071588

Fields of Study

Inflammasome and immune disordersSepsis Diagnosis and TreatmentImmune cells in cancerAnimalsSepsisMiceCalcium-Binding ProteinsMice, KnockoutMacrophagesApoptosis Regulatory ProteinsMice, Inbred C57BLT-LymphocytesCytokinesImmunity, InnateGastrointestinal MicrobiomeMale

MeSH Terms

Gastrointestinal MicrobiomeAnimalsCalcium-Binding ProteinsImmunity, InnateMacrophagesMaleMice, Inbred C57BLT-LymphocytesCytokinesMice, KnockoutSepsisApoptosis Regulatory ProteinsMice

Keywords

NLRC4SepsisChemokineSpleenInflammasomeInflammationInnate immune systemMacrophagePeritoneal cavityCytokineneutrophil