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Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints

Nucleic Acids Research(2020)10.1093/nar/gkaa616Source: DataRank Database

Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints is a research paper published in Nucleic Acids Research (2020). On theSindex it has a DataRank of 0. It has been cited 144 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access144 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (7 grants)Impact (FWCI 5.94)OA: goldTopics (47)IDs (PubMed, PMC, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (24)

Hien Zhao ORCID,Jason Le,Jill O’Moore,Rose Pitstick,Samantha Graffam

Live enrichment

PubMed:32776089 PMC:PMC7641729 OpenAlex:https://openalex.org/W3048661959

National Institutes of Health

Grant: F31 AI122592

National Science Foundation

Grant: GRFP 2015214731

NIGMS NIH HHS

Grant: R35 GM127045

National Institutes of Health

Grant: 5F31AI122592-03

Developing in vitro assays to identify small molecules that inhibit human prions

Ionis Pharmaceuticals

Broad Institute

Prion Alliance

FWCI

5.94

Citation Percentile

1.0%

Citation Trend

2020

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2026

goldLicense: cc-by

journalhttps://doi.org/10.1093/nar/gkaa616

publisherhttps://doi.org/10.1093/nar/gkaa616

publisherhttp://academic.oup.com/nar/article-pdf/48/19/10615/34133459/gkaa616.pdf

repositoryhttps://pubmed.ncbi.nlm.nih.gov/32776089

journalhttps://scholarworks.umt.edu/biopharm_pubs/71

Fields of Study

Prion Diseases and Protein MisfoldingTrace Elements in HealthNeurological diseases and metabolism0301 basic medicine0303 health sciences03 medical and health sciencesAnimalsBrainCell LineMiceMice, Inbred C57BLOligonucleotides, AntisensePrion DiseasesPrion ProteinsRNAi Therapeutics

MeSH Terms

RNAi TherapeuticsPrion ProteinsAnimalsBrainCell LineMice, Inbred C57BLOligonucleotides, AntisensePrion DiseasesMice

Keywords

DiseaseNeuropathologyNeuroinflammationBiologyBiomarkerDosingKnockout mouseImmunologyPharmacologyInternal medicineMedicineGeneticsGeneNAR Breakthrough ArticleBrainOligonucleotides, AntisensePrion ProteinsCell LinePrion DiseasesMice, Inbred C57BLMiceRNAi TherapeuticsAnimals

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being