The IntAct database: efficient access to fine-grained molecular interaction data is a dataset published in Nucleic Acids Research (2021). On theSindex it has a DataRank of 4.3, placing it in the top 5.1% of the data-sharing corpus. It has been cited 391 times, with 100 citing works in its 1-hop citation network. Its calibrated FAIR score is 77/100.
Ranks in the top 5% for downstream scientific impact
DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Full FAIR picture · advisory
The headline score is computed from the scored criteria — the fact-shaped checks (a repository, an accession, a licence) that two independent models agree on. The advisory criteria below are real FAIR guidance but rest on judgment calls that models read differently, so they inform without moving the number.
“all data is freely available through the web interface, API, and from https://www.ebi.ac.uk/intact/download under the CC BY 4.0 licence.”
The strongest identifier is a URL (https://www.ebi.ac.uk/intact/download), which is not a persistent identifier scheme.
RDA-F1-01D — FAIR Data Maturity Model: 'Data is identified by a persistent identifier' (priorit · RDA-F1-02D — FAIR Data Maturity Model: 'Data is identified by a globally unique identifier' · FsF-F1-02D — F-UJI/FAIRsFAIR: 'Data is assigned a persistent identifier'
“The IntAct molecular interaction database (https://www.ebi.ac.uk/intact) is a curated resource of molecular interactions”— not found in the paper; verdict downgraded
The IntAct database is named as the repository holding the data. [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (3/5 passes agreed)]
RDA-F4-01M — FAIR Data Maturity Model: metadata is offered so it can be harvested and indexed ( · NIH DMS Policy Element 4 (NOT-OD-21-014) — name the repository where data will be archived · NSTC Desirable Characteristics of Data Repositories (2022) — 'Long-Term Sustainability', 'Reten
“all data is freely available through the web interface, API, and from https://www.ebi.ac.uk/intact/download under the CC BY 4.0 licence.”
The dataset identifier (URL) appears only in the body text, not in the reference list.
FORCE11 Joint Declaration of Data Citation Principles (2014) — data should be cited as a first- · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes · FsF-F3-01M — F-UJI: 'Metadata includes the identifier of the data it describes'
Advisory · not in the published score
“IntAct is open source, open data. The source code is available from https://github.com/intact-portal , all data is freely available through the web interface, API, and from https://www.ebi.ac.uk/intact/download under the CC BY 4.0 licence.”
The statement points to the IntAct repository's download page, a persistent link to the data repository. [majority verdict 'yes' (3/5 passes agreed)]
Colavizza, Hrynaszkiewicz, Staden, Whitaker & McGillivray (2020), 'The citation advantage of li · Springer Nature research data policy — Data Availability Statements: standard statement templat · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes
“Data Content Since the last IntAct NAR publication, data content has grown from 408 000 (Jamuary 2014) to 1 114 500 (June 2021)) interaction evidences, and the number of referenced publications has risen from 12 500 to 22 500.”— not found in the paper; verdict downgraded
The dataset is described in running prose, without an itemised inventory or table. [downgraded to 'no' — no verifiable quote from the paper] [majority verdict 'no' (4/5 passes agreed)]
RDA-F2-01M — 'Rich metadata is provided to allow discovery' (priority Essential) · FsF-F2-01M — F-UJI: 'Metadata includes descriptive core elements to support data findability' · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data'
“all data is freely available through the web interface, API, and from https://www.ebi.ac.uk/intact/download under the CC BY 4.0 licence.”
The data are stated to be freely available with no preconditions.
RDA-A1.1-01D — 'Data is accessible through a free access protocol' · FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · NSTC Desirable Characteristics of Data Repositories (2022) — 'Free and Easy Access'
Advisory · not in the published score
“all data is freely available through the web interface, API, and from https://www.ebi.ac.uk/intact/download under the CC BY 4.0 licence.”
The paper labels the data as 'freely available', which is an explicit access-level label.
FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · RDA-A1-01M — metadata contains information to enable the user to get access to the data · COAR Controlled Vocabularies — Access Rights v1.0 (open / embargoed / restricted / metadata-onl
“The IntAct database provides a curated resource of molecular interactions, derived from the scientific literature and from direct data depositions.”— not found in the paper; verdict downgraded
The data are not sensitive human-subject data, and no gatekeeper is mentioned.
NIH Genomic Data Sharing Policy (NOT-OD-14-124) — controlled-access via a Data Access Committee · RDA-A1.2-01D — 'Data is accessible through an access protocol that supports authentication and · NIH DMS Policy Element 5 (NOT-OD-21-014) — Access, Distribution, or Reuse Considerations (conse
No statement about retention period or persistence is made. [majority verdict 'no' (3/5 passes agreed)]
NIH DMS Plan Element 4 (NOT-OD-21-014) — Data Preservation, Access, and Associated Timelines · NSTC Desirable Characteristics (2022), Organizational Infrastructure: 'Retention Policy' · RDA-A2-01M — 'Metadata is guaranteed to remain available after data is no longer available'
“the feature-rich PSI-MI XML format”
PSI-MI XML is an open, community-standard format. [majority verdict 'yes' (4/5 passes agreed)]
FsF-R1.3-02D — F-UJI: 'Data is available in a file format recommended by the target research co · RDA-R1.3-02D — data is expressed in a machine-understandable community standard · RDA-I1-01D — data uses a knowledge representation expressed in a standardised format
Advisory · not in the published score
“Curation practices and controlled vocabularies/ontologies are continuously updated, driven by the development of new methods like BioID (term in PSI-MI Ontology”— not found in the paper; verdict downgraded
The PSI-MI Ontology is a community standard vocabulary used for the data. [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (3/5 passes agreed)]
RDA-R1.3-01M — 'Metadata complies with a community standard' (priority Essential) · RDA-R1.3-01D — 'Data complies with a community standard' · RDA-I2-01M — '(Meta)data use vocabularies that follow FAIR principles'
No identifiers for external resources that the data depend on are provided. [majority verdict 'no' (4/5 passes agreed)]
RDA-I3-01M — '(meta)data include references to other (meta)data' · RDA-I3-03M — 'metadata includes qualified references to other metadata' · FsF-I3-01M — F-UJI: 'Metadata includes links between the data and its related entities'
“under the CC BY 4.0 licence.”
CC BY 4.0 is an open standard licence.
RDA-R1.1-01M — 'Metadata includes information about the licence under which the data can be reu · RDA-R1.1-02M — 'Metadata refers to a standard reuse licence' · RDA-R1.1-03M — 'Metadata refers to a machine-understandable reuse licence'
“as of August 2021”
A date is provided to pin the snapshot, but no version token.
DataCite Metadata Schema 4.6 — the 'Version' property · RDA-R1.2-01M — provenance information (which version was used is provenance) · NSTC Desirable Characteristics of Data Repositories (2022) — 'Provenance', 'Retention Policy'
“The source code is available from https://github.com/intact-portal”
A code-forge URL is provided for the study's own code.
NIH DMS Policy Element 2 (NOT-OD-21-014) — 'Related Tools, Software and/or Code' · FAIR4RS Principles v1.0 (Chue Hong et al., 2022; RDA/FORCE11/ReSA) — FAIR Principles for Resear · FORCE11 Software Citation Principles (Smith, Katz & Niemeyer, 2016, PeerJ CS 2:e86)
“Open Targets [OTAR-044, OTAR02-048, OTAR02-066]; Wellcome Trust [Biomedical Resources grants INVAR #3367 and 218294, and Centre grant 203149]”
Award numbers are given for multiple funders.
DataCite Metadata Schema 4.6 — 'FundingReference' property (funderName, funderIdentifier, award · Crossref Funder Registry — canonical funder identifiers for funding metadata · RDA-F2-01M — rich metadata provided to allow discovery (funding is part of the descriptive reco
Advisory · not in the published score
“members of the International Molecular Exchange Consortium (IMEx) have collaboratively curated molecular interaction data from the scientific literature and from direct data depositions”— not found in the paper; verdict downgraded
The production is described in generic terms without naming specific instruments or software. [downgraded to 'no' — no verifiable quote from the paper] [majority verdict 'no' (2/5 passes agreed)]
RDA-R1.2-01M — 'Metadata includes provenance information according to community- specific standa · FsF-R1.2-01M — F-UJI: 'Metadata includes provenance information about data creation or generati · W3C PROV-O (W3C Recommendation, 2013) — the entity/activity/agent model of provenance
No documentation object (README, codebook) is named as accompanying the data.
RDA-R1-01M — '(Meta)data are richly described with a plurality of accurate and relevant attribu · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data' · NIH DMS Policy Element 3 (NOT-OD-21-014) — Standards (documentation and metadata to accompany t
Calibrated FAIR score — a parallel quality metric, independent of the DataRank citation score. See the full evaluation →
Base Score Contribution
0.896
From this paper's citation signal
Citation Network Contribution
3.4
From 100 citing papers with measurable signal
Ranked by each citer's contribution to N(p) — log1p(Cq) divided by its reference count — out of 100 citers.
Open Targets
Grant: OTAR-044
Open Targets
Grant: OTAR02-048
Open Targets
Grant: OTAR02-066
Wellcome Trust
Grant: 3367
Wellcome Trust
Grant: 218294
ProCos: Protein co-regulation scores as a new resource for systematic and large-scale protein function annotation
Wellcome Trust
Grant: 203149
Italian Association for Cancer Research
Grant: 20322
Institut Français de Bioinformatique
Grant: ANR-11-INBS-0013
NIGMS
Grant: GM123126
National Institutes of Health
Grant: 5R01GM123126-03
Enhancing the International Molecular Exchange (IMEx): Providing an Improved Community-Oriented Molecular Interactions Resource
European Commission
Grant: 842490
Mapping and modulating integrin mediated interactions
Fields of Study
Keywords