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Single-molecule conformational dynamics of a transcription factor reveals a continuum of binding modes controlling association and dissociation

Nucleic Acids Research(2021)10.1093/nar/gkab874Source: DataRank Database

Single-molecule conformational dynamics of a transcription factor reveals a continuum of binding modes controlling association and dissociation is a research paper published in Nucleic Acids Research (2021). On theSindex it has a DataRank of 0. It has been cited 30 times.

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Open Access30 citations

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Enrichment:Funding (4 grants)OA: goldTopics (45)IDs (PubMed, PMC)Annotations (2)

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Authors (4)

Wei Lu ORCID,Peter G. Wolynes ORCID,Elizabeth A. Komives ORCID,Wei Chen ORCID

Live enrichment

PubMed:34614173 PMC:PMC8565325

NIH

Grant: P01GM071862

Mathers Foundation

Grant: MF-2012-01149

Ministry of Education

Grant: 1061110016

National Institutes of Health

Grant: 5P01GM071862-02

IkB/NF-kB Recognition In Silico, In Vitro and In Vivo

goldLicense: CC BY NC

publisherhttps://academic.oup.com/nar/article-pdf/49/19/11211/41071113/gkab874.pdf

publisherhttp://academic.oup.com/nar/article-pdf/49/19/11211/41071113/gkab874.pdf

repositoryhttp://europepmc.org/pmc/articles/PMC8565325

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8565325

Europe_PMChttps://europepmc.org/articles/PMC8565325

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

AnimalsHumansMiceBiotinAvidinInterferonsDNAFluorescence Resonance Energy TransferTranscription, GeneticGene Expression RegulationBinding SitesProtein BindingTranscription Factor RelAProtein Interaction Domains and MotifsInverted Repeat SequencesImmobilized ProteinsMolecular Dynamics SimulationNF-KappaB Inhibitor alphaProtein Conformation, alpha-HelicalProtein Conformation, beta-StrandSingle Molecule Imaging

Keywords

Protein Conformation, alpha-HelicalBinding SitesInverted Repeat SequencesTranscription Factor RelABiotinDNAMolecular Dynamics SimulationAvidinSingle Molecule ImagingMiceImmobilized ProteinsGene Expression RegulationNF-KappaB Inhibitor alphaFluorescence Resonance Energy TransferAnimalsHumansProtein Conformation, beta-StrandProtein Interaction Domains and MotifsInterferonsMolecular BiologyProtein Binding