Exploration and analysis of R-loop mapping data with RLBase is a dataset published in Nucleic Acids Research (2022). On theSindex it has a DataRank of 0.555, placing it in the top 35.2% of the data-sharing corpus. It has been cited 13 times, with 11 citing works in its 1-hop citation network. Its calibrated FAIR score is 60/100.
Ranks in the top 35% for downstream scientific impact
DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Full FAIR picture · advisory
The headline score is computed from the scored criteria — the fact-shaped checks (a repository, an accession, a licence) that two independent models agree on. The advisory criteria below are real FAIR guidance but rest on judgment calls that models read differently, so they inform without moving the number.
“RLBase URL: https://gccri.bishop-lab.uthscsa.edu/rlbase/”
The strongest identifier given is a web URL, which is not a persistent identifier scheme.
RDA-F1-01D — FAIR Data Maturity Model: 'Data is identified by a persistent identifier' (priorit · RDA-F1-02D — FAIR Data Maturity Model: 'Data is identified by a globally unique identifier' · FsF-F1-02D — F-UJI/FAIRsFAIR: 'Data is assigned a persistent identifier'
“upload of all data to the RLBase Amazon Web Services (AWS) S3 bucket”
The data are held in an AWS S3 bucket, which is a cloud storage service, not a named repository. [majority verdict 'partial' (4/5 passes agreed)]
RDA-F4-01M — FAIR Data Maturity Model: metadata is offered so it can be harvested and indexed ( · NIH DMS Policy Element 4 (NOT-OD-21-014) — name the repository where data will be archived · NSTC Desirable Characteristics of Data Repositories (2022) — 'Long-Term Sustainability', 'Reten
“RLBase URL: https://gccri.bishop-lab.uthscsa.edu/rlbase/”
The dataset's identifier (URL) appears only in the body text, not as a reference-list entry. [majority verdict 'partial' (4/5 passes agreed)]
FORCE11 Joint Declaration of Data Citation Principles (2014) — data should be cited as a first- · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes · FsF-F3-01M — F-UJI: 'Metadata includes the identifier of the data it describes'
Advisory · not in the published score
“Data availability. All data are made available through the RLHub R/Bioconductor package and the RLBase web interface. RLBase URL: https://gccri.bishop-lab.uthscsa.edu/rlbase/ . RLHub URL: https://bioconductor.org/packages/devel/data/experiment/html/RLHub.html .”— not found in the paper; verdict downgraded
The statement points to a repository (Bioconductor/RLHub) with a link, which is a public repository record; no persistent identifier is given, but the link is to a repository. [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (3/5 passes agreed)]
Colavizza, Hrynaszkiewicz, Staden, Whitaker & McGillivray (2020), 'The citation advantage of li · Springer Nature research data policy — Data Availability Statements: standard statement templat · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes
“RLBase contains standardized and reprocessed R-loop mapping data from 693 public samples (RLBase v1.0).”— not found in the paper; verdict downgraded
The dataset's content is described in a single sentence in running prose, without an itemised inventory or section. [downgraded to 'no' — no verifiable quote from the paper]
RDA-F2-01M — 'Rich metadata is provided to allow discovery' (priority Essential) · FsF-F2-01M — F-UJI: 'Metadata includes descriptive core elements to support data findability' · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data'
“All data are made available through the RLHub R/Bioconductor package and the RLBase web interface.”
The text gives a route to the data with no stated precondition; the data are publicly available without any requirement. [majority verdict 'yes' (4/5 passes agreed)]
RDA-A1.1-01D — 'Data is accessible through a free access protocol' · FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · NSTC Desirable Characteristics of Data Repositories (2022) — 'Free and Easy Access'
Advisory · not in the published score
“All data are made available through the RLHub R/Bioconductor package and the RLBase web interface.”
The text describes the access action (made available via RLHub and RLBase) but does not apply an explicit access-level label from the standard vocabulary. [majority verdict 'partial' (2/5 passes agreed)]
FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · RDA-A1-01M — metadata contains information to enable the user to get access to the data · COAR Controlled Vocabularies — Access Rights v1.0 (open / embargoed / restricted / metadata-onl
The data are not sensitive and no gatekeeper is named.
NIH Genomic Data Sharing Policy (NOT-OD-14-124) — controlled-access via a Data Access Committee · RDA-A1.2-01D — 'Data is accessible through an access protocol that supports authentication and · NIH DMS Policy Element 5 (NOT-OD-21-014) — Access, Distribution, or Reuse Considerations (conse
“All data are made available through the RLHub R/Bioconductor package and the RLBase web interface.”
The text states that the data are currently available but does not specify how long they will persist. [majority verdict 'partial' (3/5 passes agreed)]
NIH DMS Plan Element 4 (NOT-OD-21-014) — Data Preservation, Access, and Associated Timelines · NSTC Desirable Characteristics (2022), Organizational Infrastructure: 'Retention Policy' · RDA-A2-01M — 'Metadata is guaranteed to remain available after data is no longer available'
“RLBase sample alignment files (‘BAM’ format)”
BAM is a community-standard open format for alignment data.
FsF-R1.3-02D — F-UJI: 'Data is available in a file format recommended by the target research co · RDA-R1.3-02D — data is expressed in a machine-understandable community standard · RDA-I1-01D — data uses a knowledge representation expressed in a standardised format
Advisory · not in the published score
No data or metadata community standard is named in the text.
RDA-R1.3-01M — 'Metadata complies with a community standard' (priority Essential) · RDA-R1.3-01D — 'Data complies with a community standard' · RDA-I2-01M — '(Meta)data use vocabularies that follow FAIR principles'
“All accessions for data used in RLBase are listed in Supplementary Table S1 of our previous publication ( 12 ).”
The paper does not provide a specific identifier (accession, DOI, RRID) for any external resource; it only references a supplementary table of a previous publication. [majority verdict 'no' (3/5 passes agreed)]
RDA-I3-01M — '(meta)data include references to other (meta)data' · RDA-I3-03M — 'metadata includes qualified references to other metadata' · FsF-I3-01M — F-UJI: 'Metadata includes links between the data and its related entities'
No license is explicitly stated for the data; only the software is licensed under MIT.
RDA-R1.1-01M — 'Metadata includes information about the licence under which the data can be reu · RDA-R1.1-02M — 'Metadata refers to a standard reuse licence' · RDA-R1.1-03M — 'Metadata refers to a machine-understandable reuse licence'
“RLBase v1.0”— not found in the paper; verdict downgraded
The paper explicitly states a version token for the data. [downgraded to 'partial' — no verifiable quote from the paper]
DataCite Metadata Schema 4.6 — the 'Version' property · RDA-R1.2-01M — provenance information (which version was used is provenance) · NSTC Desirable Characteristics of Data Repositories (2022) — 'Provenance', 'Retention Policy'
“https://github.com/Bishop-Laboratory/RLBase-data”
A machine-resolvable locator (GitHub URL) is given for the study's custom code.
NIH DMS Policy Element 2 (NOT-OD-21-014) — 'Related Tools, Software and/or Code' · FAIR4RS Principles v1.0 (Chue Hong et al., 2022; RDA/FORCE11/ReSA) — FAIR Principles for Resear · FORCE11 Software Citation Principles (Smith, Katz & Niemeyer, 2016, PeerJ CS 2:e86)
“R01CA152063”
Specific grant numbers are provided for the funding sources.
DataCite Metadata Schema 4.6 — 'FundingReference' property (funderName, funderIdentifier, award · Crossref Funder Registry — canonical funder identifiers for funding metadata · RDA-F2-01M — rich metadata provided to allow discovery (funding is part of the descriptive reco
Advisory · not in the published score
“reads were quantified using the salmon pseudo aligner”
The paper names specific tools and algorithms (salmon, featureCounts, DESeq2) used in the data production pipeline. [majority verdict 'yes' (3/5 passes agreed)]
RDA-R1.2-01M — 'Metadata includes provenance information according to community- specific standa · FsF-R1.2-01M — F-UJI: 'Metadata includes provenance information about data creation or generati · W3C PROV-O (W3C Recommendation, 2013) — the entity/activity/agent model of provenance
No documentation object (e.g., README, data dictionary) is mentioned as accompanying the data, and no variable-definition table appears in the article.
RDA-R1-01M — '(Meta)data are richly described with a plurality of accurate and relevant attribu · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data' · NIH DMS Policy Element 3 (NOT-OD-21-014) — Standards (documentation and metadata to accompany t
Calibrated FAIR score — a parallel quality metric, independent of the DataRank citation score. See the full evaluation →
Base Score Contribution
0.396
From this paper's citation signal
Citation Network Contribution
0.159
From 10 citing papers with measurable signal
Ranked by each citer's contribution to N(p) — log1p(Cq) divided by its reference count — out of 11 citers.
NIH/NCI
Grant: R01CA152063
NIH/NCI
Grant: 1R01CA241554
CPRIT
Grant: RP150445
SU2C-CRUK Pediatric Cancer New Discoveries Challenge Team
Grant: SU2C #RT6187
NIH/NIA
Grant: F31AG072902
NIH
Grant: GM139549
DOD
Grant: CDMRP PR181598
NCI NIH HHS
Grant: P30 CA054174
NCI NIH HHS
Grant: R01 CA241554
NIGMS NIH HHS
Grant: R35 GM139549
National Institutes of Health
Grant: 5R35GM139549-04
Understanding the mechanisms underlying R-loop biogenesis and resolution in mammals
National Institutes of Health
Grant: 5F31AG072902-02
The dynamics and impact of R-loops in epigenetic stability and aging
National Institutes of Health
Grant: 5R01CA241554-04
Dysregulated transcription processes in Ewing sarcoma
National Institutes of Health
Grant: 1R13AG013039-01
1995 SUMMER INSTITUTE IN GERIATRIC MEDICINE
National Institutes of Health
Grant: 5R01CA152063-04
Improving etoposide treatment of Ewing's sarcoma
FWCI
1.01
Citation Percentile
0.7%
Citation Trend
Fields of Study
MeSH Terms
Keywords
Sustainable Development Goals