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Novobiocin blocks nucleic acid binding to Polθ and inhibits stimulation of its ATPase activity

Nucleic Acids Research(2023)10.1093/nar/gkad727Source: DataRank Database

Novobiocin blocks nucleic acid binding to Polθ and inhibits stimulation of its ATPase activity is a research paper published in Nucleic Acids Research (2023). On theSindex it has a DataRank of 0. It has been cited 30 times.

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Open Access30 citations

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uniprot nct pdb

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Enrichment:Funding (10 grants)OA: goldTopics (20)IDs (PubMed, PMC)Annotations (3)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (15)

František Filandr ORCID,Jeffrey Patterson-Fortin ORCID,Albino Bacolla ORCID,Ramya Ravindranathan ORCID,Jia Zhou ORCID

Live enrichment

PubMed:37665033 PMC:PMC10570058

National Institutes of Health

Grant: P01 CA092584

National Cancer Institute

Grant: R35 CA220430

Cancer Prevention and Research Institute of Texas

Grant: RP180813

Robert A. Welch Chemistry Chair

Grant: G-0010

Cancer Research UK

Grant: 24759

National Institutes of Health

Grant: 3P01CA092584-19S1

Structural Cell Biology of DNA Repair Machines

National Institutes of Health

Grant: 5R35CA220430-02

Mesocale And Nanoscale Technologies Integrated by Structures for DNA Repair Complexes (MANTIS-DRC)

Breast Cancer Research Foundation

Lustgarten Foundation

Ludwig Center at Harvard

goldLicense: cc-by-nc

publisherhttps://academic.oup.com/nar/advance-article-pdf/doi/10.1093/nar/gkad727/51336871/gkad727.pdf

publisherhttps://academic.oup.com/nar/article-pdf/51/18/9920/51975352/gkad727.pdf

repositoryhttps://escholarship.org/content/qt74z5755k/qt74z5755k.pdf

repositoryhttps://www.osti.gov/servlets/purl/2470682

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10570058/pdf/gkad727.pdf

Fields of Study

0301 basic medicine03 medical and health sciences

MeSH Terms

HumansNeoplasmsNovobiocinDNA-Directed DNA PolymeraseDNA, Single-StrandedDNA ReplicationAdenosine TriphosphatasesDNA Polymerase theta

Keywords

Adenosine TriphosphatasesDNA ReplicationNucleic Acid EnzymesNeoplasms610HumansDNA, Single-StrandedDNA-Directed DNA PolymeraseDNA Polymerase thetaNovobiocin

Novobiocin blocks nucleic acid binding to Polθ and inhibits stimulation of its ATPase activity

FAIR Checklist

Authors (15)

Funding (10 grants)

Open Access

Topics

Annotations (Europe PMC)