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Genomic transcription factor binding site selection is edited by the chromatin remodeling factor CHD4

Nucleic Acids Research(2024)10.1093/nar/gkae025Source: DataRank Database

Genomic transcription factor binding site selection is edited by the chromatin remodeling factor CHD4 is a research paper published in Nucleic Acids Research (2024). On theSindex it has a DataRank of 0.485. It has been cited 14 times, with 13 citing works in its 1-hop citation network.

N/A

0.485DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access14 citations · 13 citing works in its network

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Data availability

Repositories this paper deposited data in (declared in PubMed).

GEOGSE201797 GSE201798 GSE201799 GSE201800 GSE201801

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (11 grants)OA: goldTopics (61)IDs (PubMed, PMC, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 84%Citation Network 16%

Base Score Contribution

0.406

From this paper's citation signal

Citation Network Contribution

0.0792

From 7 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 13 citers.

CHD4 drives gastric cancer metastasis via MYH9/GSK3β/β-catenin axis and WNT/EMT pathway activation
Cancer Letters202510 citations67 referencesContributes 0.036
Chromatin-dependent motif syntax defines differentiation trajectories
bioRxiv (Cold Spring Harbor Laboratory)20246 citations140 referencesContributes 0.014
Chromatin-dependent motif syntax defines differentiation trajectories
Molecular Cell202510 citations191 referencesContributes 0.013
How ATP-Dependent Chromatin Remodeling Complexes Regulate Vertebrate Embryonic Development
International Journal of Molecular Sciences20262 citations120 referencesContributes 0.009
The chromatin remodeller CHD4 regulates transcription factor binding to both prevent activation of silent enhancers and maintain active regulatory elements
bioRxiv (Cold Spring Harbor Laboratory)20251 citations95 referencesContributes 0.007

Authors (8)

Deepak Poduval ORCID,Sara A. Grimm ORCID,Aerica Nagornyuk,Sakuntha Gunarathna ORCID,Takashi Shimbo ORCID

Live enrichment

PubMed:38281186 PMC:PMC11039999 OpenAlex:https://openalex.org/W4391290718

National Institutes of Health

Grant: ES101965

National Institutes of Health

Grant: R01GM148729

National Institutes of Health

Grant: P20GM104360

Intramural NIH HHS

Grant: Z01 ES101965

National Institutes of Health

Grant: 1ZIAES101965-08

Eukaryotic Transcriptional Regulation

National Institutes of Health

Grant: 3P20GM104360-07S1

Mechanism of Tumor Suppressor Function of Progesterone Receptor in Breast Cancer

National Institutes of Health

Grant: 5P20GM104360-05

Center for Biomedical Research Excellence, Epigenomics of Development and Disease

National Institutes of Health

Grant: 5R01GM148729-03

Role of nucleosome architecture in cellular reprogramming

Japan Society for the Promotion of Science

University of North Dakota School of Medicine and Health Sciences

Intramural Research Program of the National Institute of Environmental Health Sciences

goldLicense: cc-by

journalhttps://academic.oup.com/nar/advance-article-pdf/doi/10.1093/nar/gkae025/56440092/gkae025.pdf

publisherhttps://academic.oup.com/nar/advance-article-pdf/doi/10.1093/nar/gkae025/56440092/gkae025.pdf

publisherhttps://academic.oup.com/nar/advance-article-pdf/doi/10.1093/nar/gkae025/57313446/gkae025.pdf

journalhttps://doi.org/10.1093/nar/gkae025

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38281186

Fields of Study

Genomics and Chromatin DynamicsEpigenetics and DNA MethylationRNA modifications and cancer0301 basic medicine03 medical and health sciencesFemaleHumansBinding SitesBreast NeoplasmsCell Line, TumorCellular ReprogrammingChromatinChromatin Assembly and DisassemblyEnhancer Elements, GeneticGATA3 Transcription FactorMi-2 Nucleosome Remodeling and Deacetylase ComplexNucleosomesProtein BindingTranscription Factors

MeSH Terms

Binding SitesBreast NeoplasmsChromatinEnhancer Elements, GeneticFemaleHumansNucleosomesProtein BindingTranscription FactorsChromatin Assembly and DisassemblyCell Line, TumorGATA3 Transcription FactorMi-2 Nucleosome Remodeling and Deacetylase ComplexCellular Reprogramming

Keywords

BiologyTranscription factorChromatinGeneticsChromatin remodelingSelection (genetic algorithm)DNA binding siteComputational biologyCell biologyDNAPromoterGeneGene expressionBinding SitesGene regulation, Chromatin and EpigeneticsBreast NeoplasmsGATA3 Transcription FactorCellular ReprogrammingChromatin Assembly and DisassemblyArticleNucleosomesEnhancer Elements, GeneticCell Line, TumorHumansFemaleMi-2 Nucleosome Remodeling and Deacetylase ComplexProtein BindingTranscription Factors

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being