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Direct delivery of Cas-embedded cytosine base editors as ribonucleoprotein complexes for efficient and accurate editing of clinically relevant targets

Nucleic Acids Research(2024)10.1093/nar/gkae1217Source: DataRank Database

Direct delivery of Cas-embedded cytosine base editors as ribonucleoprotein complexes for efficient and accurate editing of clinically relevant targets is a research paper published in Nucleic Acids Research (2024). On theSindex it has a DataRank of 0.297. It has been cited 5 times, with 4 citing works in its 1-hop citation network.

N/A

0.297DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access5 citations · 4 citing works in its network

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Linked data & code

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Data availability

Repositories this paper deposited data in (declared in PubMed).

BioProjectPRJNA1096026

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 0.82)OA: goldTopics (43)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 90%Citation Network 10%

Base Score Contribution

0.269

From this paper's citation signal

Citation Network Contribution

0.0283

From 3 citing papers with measurable signal

Learn more about DataRank methodology →

Top 4 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 4 citers.

Developing safe and efficient CGBE editor based on Cas-embedding strategy
Synthetic and Systems Biotechnology20251 citations34 referencesContributes 0.020
Advances in CRISPR Base Editing: From Molecular Evolution to Therapeutic Applications in Genomic Medicine
Journal of Cellular and Molecular Medicine20262 citations112 referencesContributes 0.010
Retinal gene therapies for inherited ocular diseases: Translational delivery strategies from bench to bedside
Journal of Controlled Release20261 citations226 referencesContributes 0.003
Development of CRISPR/Cas9 based precision genome editing tools in grouper in vitro and in vivo
Aquaculture20260 citations54 referencesContributes 0.000

Authors (9)

Jing Zeng ORCID,Pengpeng Liu ORCID,My Anh Nguyen,Diego Suchenski Loustaunau,Daniel E. Bauer ORCID

Live enrichment

PubMed:39676659 PMC:PMC11724287 OpenAlex:https://openalex.org/W4405453382

National Institutes of Health

Grant: R01AI150478

National Institutes of Health

Grant: R01GM118474

Doris Duke Foundation

Grant: DDF #2022092

National Institutes of Health

Grant: 5R01AI150478-09

Structurally dissecting APOBEC3's for HIV-1 restriction and beyond

National Institutes of Health

Grant: 1R01GM118474-01

Structurally dissecting APOBEC3's for HIV-1 restriction

University of Massachusetts Chan Medical School

FWCI

0.82

Citation Percentile

0.7%

Citation Trend

2025

2026

goldLicense: cc-by-nc

journalhttps://academic.oup.com/nar/advance-article-pdf/doi/10.1093/nar/gkae1217/61196188/gkae1217.pdf

publisherhttps://academic.oup.com/nar/advance-article-pdf/doi/10.1093/nar/gkae1217/61196188/gkae1217.pdf

publisherhttps://academic.oup.com/nar/article-pdf/53/1/gkae1217/61196188/gkae1217.pdf

journalhttps://doi.org/10.1093/nar/gkae1217

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39676659

Fields of Study

CRISPR and Genetic EngineeringCytomegalovirus and herpesvirus researchRNA regulation and disease0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Gene EditingCRISPR-Associated Protein 9Anemia, Sickle CellAnimalsCarrier ProteinsCytosineHumansRibonucleoproteinsMiceHEK293 CellsCRISPR-Cas Systems

Keywords

Genome editingBiologyRibonucleoproteinCas9Bystander effectStem cellElectroporationComputational biologyCRISPRCell biologyMolecular biologyRNAGeneGeneticsImmunologyGene EditingAnemia, Sickle CellNucleic Acid TherapeuticsCytosineMiceHEK293 CellsRibonucleoproteinsHumansAnimalsCRISPR-Cas SystemsCarrier Proteins

Sustainable Development Goals

SDG 0: Good health and well-being

Direct delivery of Cas-embedded cytosine base editors as ribonucleoprotein complexes for efficient and accurate editing of clinically relevant targets

FAIR Checklist

DataRank Breakdown

Top 4 citers driving the network score

Authors (9)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)