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Human selenocysteine synthase, SEPSECS, has evolved to optimize binding of a tRNA-based substrate

Nucleic Acids Research(2024)10.1093/nar/gkae875Source: DataRank Database

Human selenocysteine synthase, SEPSECS, has evolved to optimize binding of a tRNA-based substrate is a research paper published in Nucleic Acids Research (2024). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (3 grants)Impact (FWCI 0.00)OA: goldTopics (44)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Dylan Sosa ORCID,Jennifer Castillo Suchkou ORCID,Rachel L. French ORCID,Malgorzata Dobosz-Bartoszek ORCID,Kaitlyn Kiernan ORCID

Live enrichment

PubMed:39385655 OpenAlex:https://openalex.org/W4403307604

National Institute of General Medical Sciences

Grant: R01 GM097042

National Institutes of Health

Grant: 3R01GM097042-08S1

Studies on the mechanisms governing selenium incorporation into proteins - administrative supplement for acquisition of MALS-RI detector

National Institutes of Health

Grant: 3P41GM103622-19S1

The Biophysics Collaborative Access Team

FWCI

0.00

Citation Percentile

0.2%

goldLicense: cc-by

journalhttps://doi.org/10.1093/nar/gkae875

publisherhttps://doi.org/10.1093/nar/gkae875

publisherhttps://academic.oup.com/nar/article-pdf/52/21/13368/60836502/gkae875.pdf

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39385655

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11602143

Fields of Study

Selenium in Biological SystemsFolate and B Vitamins ResearchRNA modifications and cancer0301 basic medicine03 medical and health sciences

MeSH Terms

Protein Conformation, alpha-HelicalAmino Acid SequenceAmino Acyl-tRNA SynthetasesBinding SitesHumansModels, MolecularPhylogenyProtein BindingRNA, TransferSubstrate SpecificityTransferasesSelenocysteineEvolution, MolecularCatalytic Domain

Keywords

BiologyTransfer RNASelenocysteineSubstrate specificityBiochemistrySubstrate (aquarium)GeneticsComputational biologyEnzymeRNAGeneEcologyModels, MolecularProtein Conformation, alpha-HelicalBinding SitesEvolution, MolecularAmino Acyl-tRNA SynthetasesRNA, TransferTransferasesCatalytic DomainRNA and RNA-protein complexesHumansAmino Acid SequencePhylogenyProtein Binding

Sustainable Development Goals

SDG 0: Industry, innovation and infrastructure