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A post-assembly conformational change makes the SARS-CoV-2 polymerase elongation-competent

Nucleic Acids Research(2025)10.1093/nar/gkaf450Source: DataRank Database

A post-assembly conformational change makes the SARS-CoV-2 polymerase elongation-competent is a research paper published in Nucleic Acids Research (2025). On theSindex it has a DataRank of 0. It has been cited 4 times.

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Enrichment:Funding (20 grants)OA: goldTopics (22)IDs (PubMed, PMC)Annotations (1)

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Authors (17)

Arnab Das ORCID,Subhas Chandra Bera ORCID,Thomas K. Anderson ORCID,Dana Kocíncová,Hery W. Lee ORCID

Live enrichment

PubMed:40464687 PMC:PMC12135201

German Research Foundation

Grant: DFG-DU-1872/4–1

German Research Foundation

Grant: 024.003.019

BaSyC - Building a Synthetic Cell

NWO

Grant: OCENW.XL21.XL21.115

Know your enemy: deciphering coronavirus biochemical cycles from RNA synthesis to assembly

NIH

Grant: R01 AI161841-01

NIH

Grant: U19 AI171292

NIH

Grant: U19 AI171421

NIH

Grant: R01 GM067153

NIGMS

Grant: R35-GM12260

NIAID NIH HHS

Grant: R01 AI161841

German Research Foundation

Grant: DFG-DU-1872/4-1

Deutsche Forschungsgemeinschaft

Grant: unidentified

unidentified

National Institutes of Health

Grant: 1U19AI171292-01

RAPIDLY EMERGING ANTIVIRAL DRUG DEVELOPMENT INITIATIVE- AViDD CENTER (READDI-AC)

National Institutes of Health

Grant: 1F32GM012260-01

"PATHOGENESIS-RELATED" PROTEINS OF NICOTIANA

National Institutes of Health

Grant: 2R01GM067153-18

Cellular factors maintaining and reversing silencing of bacterial chromatin

National Institutes of Health

Grant: 5R01AI161841-03

Coronavirus Genome Replication

National Institutes of Health

Grant: 1U19AI171421-01

Development of outpatient antiviral cocktails against SARS-CoV-2 and other potential pandemic RNA viruses.

OCW

Interdisciplinary Center for Clinical Research (IZKF)

Alberta Ministry of Technology and Innovation

Interdisciplinary Center for Clinical Research

goldLicense: cc-by-nc

publisherhttps://doi.org/10.1093/nar/gkaf450

publisherhttps://academic.oup.com/nar/article-pdf/53/10/gkaf450/63434826/gkaf450.pdf

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12135201

Europe_PMChttps://europepmc.org/articles/PMC12135201

Europe_PMChttps://europepmc.org/articles/PMC12135201?pdf=render

Fields of Study

0301 basic medicine03 medical and health sciences

MeSH Terms

HumansViral Nonstructural ProteinsRNA, ViralVirus ReplicationProtein ConformationTranscription Elongation, GeneticRNA-Dependent RNA PolymeraseSARS-CoV-2Coronavirus RNA-Dependent RNA Polymerase

Keywords

Coronavirus RNA-Dependent RNA PolymeraseTranscription Elongation, GeneticNucleic Acid EnzymesSARS-CoV-2Protein ConformationRNA, ViralHumansViral Nonstructural ProteinsVirus ReplicationRNA-Dependent RNA PolymeraseArticle

A post-assembly conformational change makes the SARS-CoV-2 polymerase elongation-competent

FAIR Checklist

Authors (17)

Funding (20 grants)

Open Access

Topics

Annotations (Europe PMC)