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Codon specific readthrough as a mechanism of BRCA2 restoration in acquired PARP inhibitor and chemotherapy resistance

Nucleic Acids Research(2025)10.1093/nar/gkaf990Source: DataRank Database

Codon specific readthrough as a mechanism of BRCA2 restoration in acquired PARP inhibitor and chemotherapy resistance is a research paper published in Nucleic Acids Research (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (16 grants)Impact (FWCI 0.41)OA: goldTopics (34)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (20)

X. Wei Meng,Xinyan Wu ORCID,Cristina Correia ORCID,Annapoorna Venkatachalam,Karen S. Flatten

Live enrichment

PubMed:41099700 PMC:PMC12526053 OpenAlex:https://openalex.org/W4415222194

National Cancer Institute

Grant: R01 CA190423

National Cancer Institute

Grant: P50 CA136393

National Cancer Institute

Grant: U01 CA271410

National Cancer Institute

Grant: F30 CA213737

Cancer Center Support

Grant: P30 CA015083

National Institutes of Health

Grant: R03 OD34496

David F. and Margaret T. Grohne Cancer Immunology and Immunotherapy Program

Grant: T32 GM065841

NHGRI NIH HHS

Grant: T32 HG009495

Glenn Foundation for Medical Research

Mayo Clinic Center for Individualized Medicine

Mayo Foundation for Research and Education

Mayo Clinic Center for Biomedical Discovery

Mayo Clinic Center for Individualized Medicine

Mayo Clinic Center for Biomedical Discovery

Mayo Foundation for Research and Education

Glenn Foundation for Medical Research

FWCI

0.41

Citation Percentile

0.6%

Citation Trend

2026

goldLicense: cc-by-nc

journalhttps://academic.oup.com/nar/article-pdf/53/19/gkaf990/64700888/gkaf990.pdf

publisherhttps://academic.oup.com/nar/article-pdf/53/19/gkaf990/64700888/gkaf990.pdf

journalhttps://doi.org/10.1093/nar/gkaf990

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41099700

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12526053

Fields of Study

CRISPR and Genetic EngineeringPARP inhibition in cancer therapyRNA and protein synthesis mechanismsHumansDrug Resistance, NeoplasmPoly(ADP-ribose) Polymerase InhibitorsBRCA2 ProteinCell Line, TumorCodon, NonsenseCisplatinFemaleOvarian NeoplasmsProtein BiosynthesisAntineoplastic Agents

MeSH Terms

Poly(ADP-ribose) Polymerase InhibitorsAntineoplastic AgentsCisplatinFemaleHumansOvarian NeoplasmsProtein BiosynthesisCodon, NonsenseDrug Resistance, NeoplasmBRCA2 ProteinCell Line, Tumor

Keywords

BRCA2 ProteinStop codonOpen reading framePARP inhibitorGeneMutationGene knockdownNonsense mutationPolymerase