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Targeted CRISPR knockout screening identifies known and novel chemogenomic interactions between DNA damaging agents and DNA repair genes

NAR Cancer(2025)10.1093/narcan/zcaf052Source: DataRank Database

Targeted CRISPR knockout screening identifies known and novel chemogenomic interactions between DNA damaging agents and DNA repair genes is a research paper published in NAR Cancer (2025). On theSindex it has a DataRank of 0. It has been cited 2 times.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (9 grants)OA: goldTopics (9)IDs (PubMed)

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Authors (11)

James L. Elia ORCID,Vijay Menon ORCID,Spenser S. Johnson,Sofia R. Arbelaez,Sam Friedman ORCID

Live enrichment

PubMed:21097893

NIH

Grant: 1DP5OD036128-01

Therapeutic Potential of a Novel MGMT-Dependent DNA Interstrand Crosslinking Agent in the Treatment of DNA Repair Deficient Cancer

Yale SPORE in Skin Cancer

Grant: 5P50CA121974-17

CTSA

Grant: UL1 TR001863

National Brain Tumor Society

Grant: R01CA266604

National Brain Tumor Society

Grant: R01CA276186

National Brain Tumor Society

Grant: K00CA245722

National Institutes of Health

Grant: R50CA265359

NCI

Grant: P30 CA016359

National Institute of General Medical Sciences

Grant: 1S10OD030363-01A1

goldLicense: cc-by-nc

publisherhttps://doi.org/10.1093/narcan/zcaf052

publisherhttps://academic.oup.com/narcancer/article-pdf/8/1/zcaf052/66313868/zcaf052.pdf

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12783042/

https://pubmed.ncbi.nlm.nih.gov/41522810

https://pubmed.ncbi.nlm.nih.gov/41522810/

Keywords

Gene Knockout TechniquesDNA RepairCell Line, TumorManipulating DNA repair and the DNA damage response to improve cancerHumansClustered Regularly Interspaced Short Palindromic RepeatsGliomaCRISPR-Cas SystemsDNA Damage