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Integration of the rat liver micronucleus assay into a 28-day treatment protocol: testing the genotoxicity of 4 small-molecule nitrosamines with different carcinogenic potencies and tumor target specificities

Toxicological Sciences(2025)10.1093/toxsci/kfaf002Source: DataRank Database

Integration of the rat liver micronucleus assay into a 28-day treatment protocol: testing the genotoxicity of 4 small-molecule nitrosamines with different carcinogenic potencies and tumor target specificities is a research paper published in Toxicological Sciences (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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0DataRank · unranked

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Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)Impact (FWCI 0.69)OA: greenTopics (34)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Ji‐Eun Seo ORCID,Hannah Xu,Jian Yan ORCID,Pritpal Malhi ORCID,Aisar Atrakchi

Live enrichment

PubMed:39752321 PMC:PMC12442842 OpenAlex:https://openalex.org/W4406052681

Intramural FDA HHS

Grant: FD999999

NCTR

Center for Drug Evaluation and Research

Office of New Drugs Regulatory Science Research Program

FWCI

0.69

Citation Percentile

0.6%

Citation Trend

2025

greenLicense: public-domain

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12442842/

publisherhttps://academic.oup.com/toxsci/advance-article-pdf/doi/10.1093/toxsci/kfaf002/61327990/kfaf002.pdf

publisherhttps://academic.oup.com/toxsci/article-pdf/206/2/409/61327990/kfaf002.pdf

journalhttps://doi.org/10.1093/toxsci/kfaf002

Fields of Study

Water Treatment and DisinfectionCarcinogens and Genotoxicity Assessment

MeSH Terms

AnimalsCarcinogensDose-Response Relationship, DrugLiverMaleNitrosaminesReticulocytesMicronucleus TestsHepatocytesRatsRats, Transgenic

Keywords

CarcinogenMicronucleus testGenotoxicityIn vivoChemistryMicronucleusClastogenN-NitrosodimethylamineNitrosamineFlow cytometryMolecular biologyPharmacologyToxicityToxicologyBiologyBiochemistryGeneticsLiverMicronucleus assayNitrosaminesBenchmark Dose

Sustainable Development Goals

SDG 0: Good health and well-being