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Oral exposure to di(2-ethylhexyl) phthalate alters the expression of GATA6, OCT4, and CDX2 in blastocysts and decreases the rate of implantation in a mouse model

Toxicological Sciences(2025)10.1093/toxsci/kfaf057Source: DataRank Database

Oral exposure to di(2-ethylhexyl) phthalate alters the expression of GATA6, OCT4, and CDX2 in blastocysts and decreases the rate of implantation in a mouse model is a research paper published in Toxicological Sciences (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Open Access1 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)Impact (FWCI 0.42)OA: greenTopics (52)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Isabel Hernández‐Ochoa ORCID,Jodi A. Flaws ORCID,Romana A. Nowak ORCID,Lyda Yuliana Parra-Forero ORCID

Live enrichment

PubMed:40279284 PMC:PMC12198679 OpenAlex:https://openalex.org/W4409783545

National Council of Science and Technology-Mexico

Grant: 426444

National Institutes of Health

Grant: R21ES026388

National Institutes of Health

Grant: R01ES034113

NIEHS NIH HHS

Grant: R01 ES034112

FWCI

0.42

Citation Percentile

0.6%

Citation Trend

2025

greenLicense: https://academic.oup.com/pages/standard-publication-reuse-rights

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12198679/

publisherhttps://academic.oup.com/toxsci/advance-article-pdf/doi/10.1093/toxsci/kfaf057/63011627/kfaf057.pdf

publisherhttps://academic.oup.com/toxsci/article-pdf/206/1/68/63011627/kfaf057.pdf

journalhttps://doi.org/10.1093/toxsci/kfaf057

Fields of Study

Pluripotent Stem Cells ResearchEffects and risks of endocrine disrupting chemicalsReproductive Biology and FertilityAnimalsFemaleEmbryo ImplantationOctamer Transcription Factor-3Diethylhexyl PhthalateGATA6 Transcription FactorBlastocystCDX2 Transcription FactorMiceAdministration, OralHomeodomain ProteinsPlasticizersDose-Response Relationship, DrugGene Expression Regulation, Developmental

MeSH Terms

CDX2 Transcription FactorAdministration, OralAnimalsBlastocystDiethylhexyl PhthalateDose-Response Relationship, DrugFemaleEmbryo ImplantationPlasticizersHomeodomain ProteinsGene Expression Regulation, DevelopmentalOctamer Transcription Factor-3GATA6 Transcription FactorMice

Keywords

PhthalateToxicantEmbryoAndrologyBlastocystGATA6BiologyEmbryo transferEndocrinologyInternal medicineEmbryogenesisChemistryToxicityGene expressionMedicineCell biologyGeneticsCDX2embryo implantationOct4Dehp

Sustainable Development Goals

SDG 0: Good health and well-being