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Splicing of the SynGAP Carboxyl-Terminus Enables Isoform-Specific Tuning of NMDA Receptor Signaling Linked to Cognitive Function

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.18.911487Source: DataRank Database

Splicing of the SynGAP Carboxyl-Terminus Enables Isoform-Specific Tuning of NMDA Receptor Signaling Linked to Cognitive Function is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0.

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Authors (17)

Thomas K. Creson,Camilo Rojas ORCID,Sabyasachi Maity ORCID,Aliza A. Le ORCID,Julie C. Lauterborn ORCID

Live enrichment

PubMed:21097893 OpenAlex:https://openalex.org/W3000049845

National Institutes of Health

Grant: 1R01MH096847-01A1

Impact of SynGAP1 Mutations on Synapse Maturation and Cognitive Development

National Institutes of Health

Grant: 5R01MH108408-04

Evaluation of novel biomarkers of cognition in a model of sporadic developmental brain disorders and their application in efficacy testing of Ras pathway inhibitors

greenLicense: https://www.biorxiv.org/about/FAQ#license

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2020/01/19/2020.01.18.911487.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.01.18.911487

repositoryhttps://doi.org/10.1101/2020.01.18.911487

https://dx.doi.org/10.1101/2020.01.18.911487

Fields of Study

Neuroscience and Neuropharmacology ResearchRNA Research and SplicingCellular transport and secretion0301 basic medicine03 medical and health sciences

Keywords

Excitatory postsynaptic potentialNMDA receptorPostsynaptic densityLong-term potentiationNeurosciencePostsynaptic potentialDendritic spineSynaptic plasticityAMPA receptorAlternative splicingGene isoformChemistryCell biologyBiologyReceptorBiochemistryInhibitory postsynaptic potentialGeneHippocampal formation