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The Mitochondrial Permeability Transition Phenomenon Elucidated by Cryo-EM Reveals the Genuine Impact of Calcium Overload on Mitochondrial Structure and Function

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.13.991349Source: DataRank Database

The Mitochondrial Permeability Transition Phenomenon Elucidated by Cryo-EM Reveals the Genuine Impact of Calcium Overload on Mitochondrial Structure and Function is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0. It has been cited 6 times.

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Enrichment:Funding (3 grants)OA: greenTopics (29)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (6)

Jason R. Schrad ORCID,Evgeny V. Pavlov ORCID,James F. Conway ORCID,Kristin N. Parent ORCID,Jason N. Bazil ORCID

Live enrichment

PubMed:23304386 OpenAlex:https://openalex.org/W3011336222

National Institutes of Health

Grant: 5R00HL121160-05

Mechanistic Characterization of Calcium and ROS Induced Mitochondrial Dysfunction

National Institutes of Health

Grant: 1S10OD019995-01

Direct electron detecting (DED) camera

National Institutes of Health

Grant: 5R01GM110185-03

Sf6 as a model system for understanding the mechanisms of virus: host recognition

greenLicense: CC BY

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2020/03/18/2020.03.13.991349.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.03.13.991349

repositoryhttps://doi.org/10.1101/2020.03.13.991349

https://doi.org/10.1038/s41598-020-80398-8

Fields of Study

Mitochondrial Function and PathologyATP Synthase and ATPases ResearchMetabolism and Genetic Disorders0303 health sciences03 medical and health sciences

Keywords

CalciumMitochondrionMitochondrial permeability transition poreCell biologyFragmentation (computing)Inner mitochondrial membraneBiologyChemistryBiophysicsBiochemistryProgrammed cell deathApoptosisCalcium PhosphatesMembrane Potential, MitochondrialScienceQCryoelectron MicroscopyGuinea PigsRArticleMitochondria, HeartMitochondrial MembranesMedicineAnimals

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SDG 2: 2. Zero hunger