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Inhibition of Striatal-Enriched Protein Tyrosine Phosphatase (STEP) Activity Reverses Behavioral Deficits in a Rodent Model of Autism

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.17.047597Source: DataRank Database

Inhibition of Striatal-Enriched Protein Tyrosine Phosphatase (STEP) Activity Reverses Behavioral Deficits in a Rodent Model of Autism is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0.

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Enrichment:Funding (2 grants)OA: greenTopics (44)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (5)

Priya Singh ORCID,Jian Xu ORCID,Paul J. Lombroso,Pradeep Kurup,Manavi Chatterjee ORCID

Live enrichment

PubMed:21097893 OpenAlex:https://openalex.org/W3016610513

National Institutes of Health

Grant: 5R01MH052711-08

MOLECULAR AND CELLULAR ANALYSIS OF BRAIN ENRICHED PTPS

National Institutes of Health

Grant: 5R01MH091037-02

The Role of STEP in Schizophrenia

greenLicense: Elsevier TDM

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2020/04/18/2020.04.17.047597.1.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.04.17.047597

repositoryhttps://doi.org/10.1101/2020.04.17.047597

https://doi.org/10.1016/j.bbr.2020.112713

Fields of Study

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder ResearchNeurogenesis and neuroplasticity mechanisms03 medical and health sciences0302 clinical medicine

Keywords

AutismNeuroscienceSynaptic plasticityPrefrontal cortexPsychologyProtein tyrosine phosphataseNeuroplasticityDownregulation and upregulationRodentElevated plus mazeAnxietyCognitionBiologyInternal medicineDevelopmental psychologyMedicinePhosphorylationPsychiatryGeneticsReceptorMaleNeuronal PlasticityBehavior, AnimalAutism Spectrum DisorderValproic AcidProtein Tyrosine Phosphatases, Non-ReceptorMice, Inbred C57BLDisease Models, AnimalInhibition, PsychologicalMicePregnancyPrenatal Exposure Delayed EffectsExploratory BehaviorAnimalsFemaleAutistic DisorderProtein Tyrosine PhosphatasesStereotyped BehaviorSocial Behavior

Sustainable Development Goals

SDG 3: 3. Good health