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Exploration of bacterial bottlenecks and Streptococcus pneumoniae pathogenesis by CRISPRi-seq

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.22.055319Source: DataRank Database

Exploration of bacterial bottlenecks and Streptococcus pneumoniae pathogenesis by CRISPRi-seq is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0. It has been cited 6 times.

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Open Access6 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)OA: greenTopics (57)IDs (PubMed, OpenAlex)SDGs (2)

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Accessible (1/2)

Open Access

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Reusable (0/3)

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Authors (5)

Jacqueline M. Kimmey ORCID,Vincent de Bakker ORCID,Victor Nizet ORCID,Jan‐Willem Veening ORCID,Xue Liu ORCID

Live enrichment

PubMed:33120116 OpenAlex:https://openalex.org/W3018666479

National Institutes of Health

Grant: 5R01AI145325-03

C3-Dependent Intracellular Killing in Innate Immunity and Bacterial Pathogenesis

European Commission

Grant: 771534

The role of cell-to-cell variability in pneumococcal virulence and antibiotic resistance

Swiss National Science Foundation

Grant: 172861

Division site and division plane selection in the human pathogen Streptococcus pneumoniae

Swiss National Science Foundation

Grant: 185533

Fighting antimicrobial resistant infections by high-throughput discovery of biofilm-disrupting agents and mechanisms

European Commission

Grant: 847786

FLAGELLIN AEROSOL THERAPY AS AN IMMUNOMODULATORY ADJUNCT TO THE ANTIBIOTIC TREATMENT OF DRUG-RESISTANT BACTERIAL PNEUMONIA

Swiss National Science Foundation

Grant: 180541

NCCR AntiResist (phase I)

Influential Citations

Citation Trend

2020

2022

2023

greenLicense: cc-by

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2020/04/23/2020.04.22.055319.full.pdf

GREENhttps://www.biorxiv.org/content/biorxiv/early/2020/04/23/2020.04.22.055319.full.pdf

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2020/04/23/2020.04.22.055319.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.04.22.055319

repositoryhttps://doi.org/10.1101/2020.04.22.055319

Fields of Study

Pneumonia and Respiratory InfectionsCRISPR and Genetic EngineeringBacterial Infections and VaccinesBiologyMedicine0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

BiologyVirulenceStreptococcus pneumoniaeGeneMicrobiologyGeneticsBacteriabottleneckMalebacterial pathogenesisInbred C57BLMice2.1 Biological and endogenous factors2.2 Factors relating to the physical environmentClustered Regularly Interspaced Short Palindromic RepeatsAetiologyLungInbred BALB CMice, Inbred BALB CBacterialHigh-Throughput Nucleotide SequencingBiological SciencesMedical microbiology[SDV] Life Sciences [q-bio]influenza A virus superinfectionInfectious DiseasesInfluenza A virusCRISPRi-seq; Streptococcus pneumoniae; bacterial pathogenesis; bottleneck; influenza A virus superinfection; pneumoniaPneumonia & InfluenzaPneumococcalFemaleInfectionImmunologyCRISPRi-seqAdenylosuccinate SynthaseOrthomyxoviridae InfectionsOperonpneumoniaAnimalsBiomedical and Clinical SciencesPreventionHuman GenomePneumonia, PneumococcalMice, Inbred C57BLGenesGenes, BacterialBiochemistry and cell biologySuperinfectionGenetic Fitness

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Exploration of bacterial bottlenecks and Streptococcus pneumoniae pathogenesis by CRISPRi-seq

FAIR Checklist

Authors (5)

Funding (6 grants)

Impact

Open Access

Topics