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Auranofin resistance in Toxoplasma gondii decreases the accumulation of reactive oxygen species but does not target parasite thioredoxin reductase

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.23.058842Source: DataRank Database

Auranofin resistance in Toxoplasma gondii decreases the accumulation of reactive oxygen species but does not target parasite thioredoxin reductase is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0. It has been cited 1 time.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)OA: greenTopics (66)IDs (PubMed, OpenAlex)SDGs (1)

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Open Access

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Authors (9)

James A. Tirtorahardjo,Sharon Jan,Sakura S. Schweizer,Shawn A. C. Rosario,Yanmiao Du

Live enrichment

PubMed:19767382 OpenAlex:https://openalex.org/W3020713544

National Institutes of Health

Grant: 5P30CA062203-08

CORE--BIOSTATISTICS FACILITY

National Institutes of Health

Grant: 1S10OD021718-01

High-Throughput DNA Sequencer

National Institutes of Health

Grant: 1S10RR025496-01

High Throughput DNA Sequencer

National Institutes of Health

Grant: 3P30CA062203-27S1

Clinical Trial Advancement and Development for Sarcomas

National Institutes of Health

Grant: 5K08AI102989-04

Thio-dependent Antioxidants: A Novel Drug Target for Toxoplasma Gondii

National Institutes of Health

Grant: 1S10OD010794-01

PacBio RS Single Molecule, Real-Time (SMRT) DNA Sequencer

greenLicense: CC BY

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2020/04/25/2020.04.23.058842.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.04.23.058842

repositoryhttps://doi.org/10.1101/2020.04.23.058842

https://doi.org/10.3389/fcimb.2021.618994

Fields of Study

Toxoplasma gondii Research StudiesAutophagy in Disease and TherapyCytomegalovirus and herpesvirus research0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

AuranofinThioredoxin reductaseReactive oxygen speciesBiologyThioredoxinToxoplasma gondiiOxidative stressPlasmodium falciparumWild typeSuperoxide dismutaseReductaseBiochemistryGeneGeneticsEnzymeImmunologyMutantMalariarepurposingCellular and Infection Microbiology0605 Microbiology (for)Animals (mesh)32 Biomedical and Clinical Sciences (for-2020)3107 Microbiology (for-2020)Parasites (mesh)Biological SciencesFoodborne IllnessQR1-502Infectious DiseasesMedical MicrobiologyFoodborne Illness (rcdc)redoxsuperoxideToxoplasma570Thioredoxin-Disulfide ReductaseThioredoxin-Disulfide Reductase (mesh)anti-parasitic0601 Biochemistry and Cell Biology (for)Antimicrobial Resistance (rcdc)MicrobiologyEmerging Infectious Diseases (rcdc)Toxoplasma (mesh)resistanceBiodefense616Animals3207 Medical Microbiology (for-2020)Biodefense (rcdc)Parasites31 Biological Sciences (for-2020)Biomedical and Clinical SciencesReactive Oxygen Species (mesh)Genetics (rcdc)Auranofin (mesh)goldEmerging Infectious DiseasesInfectious Diseases (rcdc)Antimicrobial ResistanceBiochemistry and Cell Biology

Sustainable Development Goals

SDG 3: 3. Good health