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HIV Vpr modulates the host DNA damage response at two independent steps to damage DNA and repress double-strand DNA break repair

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.26.062349Source: DataRank Database

HIV Vpr modulates the host DNA damage response at two independent steps to damage DNA and repress double-strand DNA break repair is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)OA: greenTopics (56)IDs (PubMed, OpenAlex)SDGs (2)

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Open Access

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Authors (5)

Andrew Lopez ORCID,Carina Sandoval ORCID,Randilea Nichols Doyle ORCID,Oliver I. Fregoso ORCID,Donna Li ORCID

Live enrichment

PubMed:19162232 OpenAlex:https://openalex.org/W3019712412

National Institutes of Health

Grant: 5T32GM007185-39

Research Training in Cellular and Molecular Biology

National Institutes of Health

Grant: 1K22AI122824-01A1

Regulation of HIV-1 and related lentiviruses by the DNA damage response

National Institutes of Health

Grant: 5R01AI147837-03

Defining the regulation of double-strand DNA break repair by HIV Vpr

National Institutes of Health

Grant: 1T32AI007323-01A1

MULTIDISCIPLINARY TRAINING IN MICROBIAL PATHOGENESIS

National Institutes of Health

Grant: 5R01AI147837-04

Defining the regulation of double-strand DNA break repair by HIV Vpr

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2020/04/26/2020.04.26.062349.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.04.26.062349

repositoryhttps://doi.org/10.1101/2020.04.26.062349

repositoryhttps://escholarship.org/uc/item/6qr1j8nb

Fields of Study

DNA Repair MechanismsHIV Research and TreatmentPolyomavirus and related diseases0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

DNA damageBiologyHomologous recombinationDNADNA repairDNA replicationCell biologyGenome instabilityGeneticsretrovirusesHIV InfectionsDNA damage responseVirus ReplicationDouble-Stranded2.1 Biological and endogenous factors2.2 Factors relating to the physical environmenthost-pathogen interactionsDNA Breaks, Double-StrandedlentivirusesOsteosarcomaTumorhuman immunodeficiency virusvpr Gene Products, Human Immunodeficiency VirusMedical microbiologyQR1-502Infectious DiseasesHIV/AIDSInfectionResearch Article570RNA virusvpr Gene Products1.1 Normal biological development and functioning610VprMicrobiologyCell LineCell Line, TumorHumansDNA damage checkpointsvirus-host interactionsBiomedical and Clinical SciencesDNA BreaksHIVHEK293 CellsBiochemistry and cell biologyHIV-2HIV-1Sexually Transmitted InfectionsGeneric health relevance

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being