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Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.27.064386Source: DataRank Database

Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Enrichment:Funding (10 grants)OA: greenTopics (44)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (20)

Max Emperle,Yiran Guo ORCID,Sara A. Grimm ORCID,Wendan Ren ORCID,Sabrina Adam ORCID

Live enrichment

PubMed:19767382 OpenAlex:https://openalex.org/W3021760502

National Institutes of Health

Grant: 5R35GM119721-02

Mechanistic Insights into Mammalian DNA Methylation

Deutsche Forschungsgemeinschaft

Grant: unidentified

unidentified

National Institutes of Health

Grant: 5R01CA215284-04

Determining the Role of DNA Methylation Deregulation in Oncogenesis

National Institutes of Health

Grant: 1Z01ES101965-01

Eukaryotic Transcriptional Regulation

National Institutes of Health

Grant: 5R01CA211336-05

Cancer Epigenetics: A novel PRC2 Dysregulation Mechanism in Multiple Myeloma

National Institutes of Health

Grant: 1R21ES025392-01A1

Enzymatic Conversions of Tet-mediated Oxidation Products of 5-Methylcytosine

National Institutes of Health

Grant: 1R03HS013039-01

Violence &SCI: Understanding the Rehabilitation Context

National Institutes of Health

Grant: 5R35ES031707-04

Chemical Biology of DNA and RNA Alkylation

National Institutes of Health

Grant: 3P30CA016086-42S2

Cancer Center Support Grant

National Institutes of Health

Grant: 1ZIAES101965-08

Eukaryotic Transcriptional Regulation

greenLicense: CC BY

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2020/04/29/2020.04.27.064386.full.pdf

repositoryhttps://doi.org/10.1101/2020.04.27.064386

https://doi.org/10.1038/s41467-020-17109-4

https://www.nature.com/articles/s41467-020-17109-4.pdf

Fields of Study

Epigenetics and DNA MethylationCancer-related gene regulationRNA modifications and cancer0301 basic medicine03 medical and health sciences

Keywords

DNMT3BMethyltransferaseMethylationDNA methylationBiologyGeneticsEpigenomicsCpG siteComputational biologyDNAGeneGene expressionDNA Methyltransferase 3B570SciencePrimary Immunodeficiency DiseasesArticleCell LineDNA Methyltransferase 3AEpigenesis, GeneticSubstrate SpecificityMiceStructure-Activity RelationshipGeneticX-Ray DiffractionCatalytic Domain2.1 Biological and endogenous factorsAnimalsHumansDNA (Cytosine-5-)-MethyltransferasesAetiologyEmbryonic Stem CellsEnzyme AssaysHuman GenomeQFaceMutationCpG IslandsEpigenesis

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