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Brain tissue transcriptomic analysis of SIV-infected macaques identifies several altered metabolic pathways linked to neuropathogenesis, and Poly (ADP-ribose) polymerases (PARPs) as potential therapeutic targets

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.21.109140Source: DataRank Database

Brain tissue transcriptomic analysis of SIV-infected macaques identifies several altered metabolic pathways linked to neuropathogenesis, and Poly (ADP-ribose) polymerases (PARPs) as potential therapeutic targets is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0.

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Authors (14)

Andrea S. Ramirez-Mata ORCID,James J. Dollar ORCID,David J. Nolan ORCID,Kevin White,Shannan N. Rich ORCID

Live enrichment

PubMed:21097893 OpenAlex:https://openalex.org/W3106361883

National Institutes of Health

Grant: 2R01NS063897-06

Viral evolution in peripheral macrophages and brain during progression to AIDS

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2020/07/02/2020.05.21.109140.full.pdf

repositoryhttps://doi.org/10.1101/2020.05.21.109140

https://doi.org/10.1007/s13365-020-00927-z

https://link.springer.com/content/pdf/10.1007/s13365-020-00927-z.pdf

Fields of Study

HIV Research and TreatmentCytomegalovirus and herpesvirus researchTryptophan and brain disorders0301 basic medicine03 medical and health sciences

Keywords

Simian immunodeficiency virusBiologyTranscriptomeVirusNeurodegenerationNeuropathologyVirologyImmunologyMedicineGeneGeneticsGene expressionDiseasePathologyMaleSimian Acquired Immunodeficiency SyndromeAnimalsPoly(ADP-ribose) PolymerasesCognition DisordersMacaca mulattaArticleFrontal Lobe

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SDG 2: 2. Zero hungerSDG 3: 3. Good healthSDG 0: Good health and well-being